3vhe
Crystal structure of human VEGFR2 kinase domain with a novel pyrrolopyrimidine inhibitor.Crystal structure of human VEGFR2 kinase domain with a novel pyrrolopyrimidine inhibitor.
Template:ABSTRACT PUBMED 20833055
About this StructureAbout this Structure
3vhe is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Oguro Y, Miyamoto N, Okada K, Takagi T, Iwata H, Awazu Y, Miki H, Hori A, Kamiyama K, Imamura S. Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: novel VEGFR2 kinase inhibitors binding to inactive kinase conformation. Bioorg Med Chem. 2010 Oct 15;18(20):7260-73. Epub 2010 Aug 13. PMID:20833055 doi:10.1016/j.bmc.2010.08.017