3pn3

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Template:STRUCTURE 3pn3

Crystal structure of Arabidopsis thaliana petide deformylase 1B (AtPDF1B) in complex with inhibitor 21Crystal structure of Arabidopsis thaliana petide deformylase 1B (AtPDF1B) in complex with inhibitor 21

Template:ABSTRACT PUBMED 21629676

FunctionFunction

[DEF1B_ARATH] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Has a preferred substrate specificity towards the photosystem II (PS II) D1 polypeptide.[1]

About this StructureAbout this Structure

3pn3 is a 2 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Fieulaine S, Boularot A, Artaud I, Desmadril M, Dardel F, Meinnel T, Giglione C. Trapping conformational States along ligand-binding dynamics of Peptide deformylase: the impact of induced fit on enzyme catalysis. PLoS Biol. 2011 May;9(5):e1001066. Epub 2011 May 24. PMID:21629676 doi:10.1371/journal.pbio.1001066
  1. Giglione C, Serero A, Pierre M, Boisson B, Meinnel T. Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms. EMBO J. 2000 Nov 1;19(21):5916-29. PMID:11060042 doi:10.1093/emboj/19.21.5916

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