3pp0
Crystal Structure of the Kinase domain of Human HER2 (erbB2).Crystal Structure of the Kinase domain of Human HER2 (erbB2).
About this StructureAbout this Structure
3pp0 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Aertgeerts K, Skene R, Yano J, Sang BC, Zou H, Snell G, Jennings A, Iwamoto K, Habuka N, Hirokawa A, Ishikawa T, Tanaka T, Miki H, Ohta Y, Sogabe S. Structural Analysis of the Mechanism of Inhibition and Allosteric Activation of the Kinase Domain of HER2 Protein. J Biol Chem. 2011 May 27;286(21):18756-65. Epub 2011 Mar 30. PMID:21454582 doi:10.1074/jbc.M110.206193
- ↑ Tsou YA, Chen KC, Chang SS, Wen YR, Chen CY. A possible strategy against head and neck cancer: in silico investigation of three-in-one inhibitors. J Biomol Struct Dyn. 2012 Nov 12. PMID:23140436 doi:10.1080/07391102.2012.736773