Sequence Alignment Tools

What I want:

  1. % identity vs. length of each chain and number of identical residues/chain length for each chain
  2. colors that indicate identity/similarity/difference
  3. ability to block a region of the alignment and get identity and length for that region (could cut and paste a new job ...)


JalviewJalview

Seems to be mostly an alignment editing tool.


ClustalW2 at EBIClustalW2 at EBI

ClustalW2

  • has colors but no color key
  • no % id (?!)
  • give a score but doesn't explain it.


RCSB Compare StructuresRCSB Compare Structures

  • Smith-Waterman or Needleman-Wunsch does #1,#2 but only for sequences of 3D structures.
  • Smith-Waterman shows only the aligned segments, while Needleman-Wunsch shows full length with gaps.

Swiss-Model

Why doesn't it make a model of FlgE CamJe using 1wlg?