Template:STRUCTURE 3poz

File:3poz.png

EGFR Kinase domain complexed with tak-285EGFR Kinase domain complexed with tak-285

Template:ABSTRACT PUBMED 21454582

About this StructureAbout this Structure

3poz is a 1 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Aertgeerts K, Skene R, Yano J, Sang BC, Zou H, Snell G, Jennings A, Iwamoto K, Habuka N, Hirokawa A, Ishikawa T, Tanaka T, Miki H, Ohta Y, Sogabe S. Structural Analysis of the Mechanism of Inhibition and Allosteric Activation of the Kinase Domain of HER2 Protein. J Biol Chem. 2011 May 27;286(21):18756-65. Epub 2011 Mar 30. PMID:21454582 doi:10.1074/jbc.M110.206193

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OCA