2r3r
Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitorCrystal Structure of Cyclin-Dependent Kinase 2 with inhibitor
About this StructureAbout this Structure
2r3r is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Fischmann TO, Hruza A, Duca JS, Ramanathan L, Mayhood T, Windsor WT, Le HV, Guzi TJ, Dwyer MP, Paruch K, Doll RJ, Lees E, Parry D, Seghezzi W, Madison V. Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers. 2007 Oct 15;. PMID:17937404 doi:http://dx.doi.org/10.1002/bip.20868
- ↑ Dwyer MP, Paruch K, Alvarez C, Doll RJ, Keertikar K, Duca J, Fischmann TO, Hruza A, Madison V, Lees E, Parry D, Seghezzi W, Sgambellone N, Shanahan F, Wiswell D, Guzi TJ. Versatile templates for the development of novel kinase inhibitors: Discovery of novel CDK inhibitors. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6216-9. Epub 2007 Sep 8. PMID:17904366 doi:http://dx.doi.org/10.1016/j.bmcl.2007.09.018