Template:STRUCTURE 2h89

File:2h89.png

Avian Respiratory Complex II with Malonate BoundAvian Respiratory Complex II with Malonate Bound

Template:ABSTRACT PUBMED 16935256

About this StructureAbout this Structure

2h89 is a 4 chain structure of Succinate Dehydrogenase with sequence from Gallus gallus. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1][xtra 2]

  1. Huang LS, Shen JT, Wang AC, Berry EA. Crystallographic studies of the binding of ligands to the dicarboxylate site of Complex II, and the identity of the ligand in the "oxaloacetate-inhibited" state. Biochim Biophys Acta. 2006 Sep-Oct;1757(9-10):1073-83. Epub 2006 Jul 12. PMID:16935256 doi:10.1016/j.bbabio.2006.06.015
  2. Huang LS, Sun G, Cobessi D, Wang AC, Shen JT, Tung EY, Anderson VE, Berry EA. 3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, upon oxidation by complex II, forms a covalent adduct with a catalytic base arginine in the active site of the enzyme. J Biol Chem. 2006 Mar 3;281(9):5965-72. Epub 2005 Dec 21. PMID:16371358 doi:10.1074/jbc.M511270200

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