2v0z
CRYSTAL STRUCTURE OF RENIN WITH INHIBITOR 10 (ALISKIREN)CRYSTAL STRUCTURE OF RENIN WITH INHIBITOR 10 (ALISKIREN)
About this StructureAbout this Structure
2v0z is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Rahuel J, Rasetti V, Maibaum J, Rueger H, Goschke R, Cohen NC, Stutz S, Cumin F, Fuhrer W, Wood JM, Grutter MG. Structure-based drug design: the discovery of novel nonpeptide orally active inhibitors of human renin. Chem Biol. 2000 Jul;7(7):493-504. PMID:10903938
- ↑ Rahuel J, Priestle JP, Grutter MG. The crystal structures of recombinant glycosylated human renin alone and in complex with a transition state analog inhibitor. J Struct Biol. 1991 Dec;107(3):227-36. PMID:1807356