Structure of AmpC beta-lactamase with cross-linked active site after exposure to small molecule inhibitor

File:2p9v.jpg


2p9v, resolution 1.80Å

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About this StructureAbout this Structure

2P9V is a Protein complex structure of sequences from Escherichia coli with as ligand. Active as Beta-lactamase, with EC number 3.5.2.6 Full crystallographic information is available from OCA.

ReferenceReference

O-aryloxycarbonyl hydroxamates: new beta-lactamase inhibitors that cross-link the active site., Wyrembak PN, Babaoglu K, Pelto RB, Shoichet BK, Pratt RF, J Am Chem Soc. 2007 Aug 8;129(31):9548-9. Epub 2007 Jul 12. PMID:17628063

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