TolA

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TolA proteins are located in the inner membrane.

StructureStructure

TolA comprises of three domains: domain I, from residues 1-47 including a 20-residue hydrophobic membrane spanning region; domain II, from residues 48-301, which forms a rigid helix connecting the domains either side of it; and domain III from residues 302-421, which may be involved in the function of TolA by interacting with the periplasmic or outer membrane proteins.[1]

FunctionFunction

To view related Tol entries see:To view related Tol entries see:

ReferencesReferences

  1. Levengood-Freyermuth SK, Click EM, Webster RE. Role of the carboxyl-terminal domain of TolA in protein import and integrity of the outer membrane. J Bacteriol. 1993 Jan;175(1):222-8. PMID:8416897

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Laura McCauley, Michal Harel