Peroxiredoxin
Peroxiredoxin (Prx) is an antioxidant enzyme. In the Prxs the active-site Cys is oxidized to sulfenic acid byperoxide. The Prxs are divided into typical 2-Cys Prx, atypical 2-Cys Prx and 1-Cys Prx. The images at the left and at the right correspond to one representative Prx, i.e. the crystal structure of Peroxiredoxin from rat (1qq2).
3D Structures of Peroxiredoxin3D Structures of Peroxiredoxin
1qq2 – 2Cys-Prx – rat
2c0d – 2Cys-Prx – Plasmodium falciparum
1urm – hPrx 5 (mutant) – human
2vl2, 2vl3, 2vl9 – hPrx 5
3mng – hPrx 5+DTT
2av5 – Prx dot5 C-termianl (mutant) -yeast