3fl9
Crystal structure of B. anthracis dihydrofolate reductase (DHFR) with trimethoprimCrystal structure of B. anthracis dihydrofolate reductase (DHFR) with trimethoprim
About this StructureAbout this Structure
3fl9 is a 8 chain structure of Dihydrofolate reductase with sequence from Bacillus anthracis. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Bourne CR, Bunce RA, Bourne PC, Berlin KD, Barrow EW, Barrow WW. Crystal structure of Bacillus anthracis dihydrofolate reductase with the dihydrophthalazine-based trimethoprim derivative RAB1 provides a structural explanation of potency and selectivity. Antimicrob Agents Chemother. 2009 Jul;53(7):3065-73. Epub 2009 Apr 13. PMID:19364848 doi:10.1128/AAC.01666-08