3lyr

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Template:STRUCTURE 3lyr

Human Early B-cell Factor 1 (EBF1) DNA-binding domainHuman Early B-cell Factor 1 (EBF1) DNA-binding domain

Template:ABSTRACT PUBMED 20592035

FunctionFunction

[COE1_HUMAN] Transcriptional activator which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (By similarity).

About this StructureAbout this Structure

3lyr is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Siponen MI, Wisniewska M, Lehtio L, Johansson I, Svensson L, Raszewski G, Nilsson L, Sigvardsson M, Berglund H. Structural determination of functional domains in early B-cell factor (EBF) family of transcription factors reveals similarities to Rel DNA-binding proteins and a novel dimerization motif. J Biol Chem. 2010 Aug 20;285(34):25875-9. Epub 2010 Jun 30. PMID:20592035 doi:10.1074/jbc.C110.150482

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