Anthony Noles Sandbox
Mechanism of AconitaseMechanism of Aconitase
Aconitase catalyzes the reversible isomerization of citrate and isocitrate. First, dehydration of citrate causes a proton and OH group to be removed from only the 'lower arm'[1]
Text text (PDB 2b3x).
Potential Pubmed reference [2]
ReferencesReferences
- ↑ Voet, Donald, Judith G. Voet, and Charlotte W. Pratt. Fundamentals of Biochemistry Life at the Molecular Level. New York: John Wiley & Sons, 2008. Print.
- ↑ Dupuy J, Volbeda A, Carpentier P, Darnault C, Moulis JM, Fontecilla-Camps JC. Crystal structure of human iron regulatory protein 1 as cytosolic aconitase. Structure. 2006 Jan;14(1):129-39. PMID:16407072 doi:10.1016/j.str.2005.09.009
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