3lcd

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File:3lcd.jpg

Template:STRUCTURE 3lcd

Inhibitor Bound to A DFG-In structure of the Kinase Domain of CSF-1RInhibitor Bound to A DFG-In structure of the Kinase Domain of CSF-1R

Template:ABSTRACT PUBMED 20137931

About this StructureAbout this Structure

3LCD is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Meyers MJ, Pelc M, Kamtekar S, Day J, Poda GI, Hall MK, Michener ML, Reitz BA, Mathis KJ, Pierce BS, Parikh MD, Mischke DA, Long SA, Parlow JJ, Anderson DR, Thorarensen A. Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1543-7. Epub 2010 Jan 21. PMID:20137931 doi:10.1016/j.bmcl.2010.01.078

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OCA

[1] Meyers MJ, Pelc M, Kamtekar S, Day J, Poda GI, Hall MK, Michener ML, Reitz BA, Mathis KJ, Pierce BS, Parikh MD, Mischke DA, Long SA, Parlow JJ, Anderson DR, Thorarensen A. Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1543-7. Epub 2010 Jan 21. PMID:20137931 doi:10.1016/j.bmcl.2010.01.078

[xtra 1]