3kmx

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Template:STRUCTURE 3kmx

File:3kmx.jpg

Structure of BACE bound to SCH346572Structure of BACE bound to SCH346572

Template:ABSTRACT PUBMED 20043700

About this StructureAbout this Structure

3KMX is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Wang YS, Strickland C, Voigt JH, Kennedy ME, Beyer BM, Senior MM, Smith EM, Nechuta TL, Madison VS, Czarniecki M, McKittrick BA, Stamford AW, Parker EM, Hunter JC, Greenlee WJ, Wyss DF. Application of Fragment-Based NMR Screening, X-ray Crystallography, Structure-Based Design, and Focused Chemical Library Design to Identify Novel muM Leads for the Development of nM BACE-1 (beta-Site APP Cleaving Enzyme 1) Inhibitors. J Med Chem. 2009 Dec 31. PMID:20043700 doi:10.1021/jm901472u

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OCA

[1] Wang YS, Strickland C, Voigt JH, Kennedy ME, Beyer BM, Senior MM, Smith EM, Nechuta TL, Madison VS, Czarniecki M, McKittrick BA, Stamford AW, Parker EM, Hunter JC, Greenlee WJ, Wyss DF. Application of Fragment-Based NMR Screening, X-ray Crystallography, Structure-Based Design, and Focused Chemical Library Design to Identify Novel muM Leads for the Development of nM BACE-1 (beta-Site APP Cleaving Enzyme 1) Inhibitors. J Med Chem. 2009 Dec 31. PMID:20043700 doi:10.1021/jm901472u

[xtra 1]