Proteopedia:Table of Contents

INTRODUCTIONINTRODUCTION

• Introduction to the Chemistry of Life
• Water
  • Water_in_macromolecular_models
• Key chemical concepts for Structural Biology
  • Cation-pi interactions

BIOMOLECULESBIOMOLECULES

• Nucleotides, Nucleic Acids, and Genetic Information
  • Z-DNA
• Amino_Acids
• Proteins: Primary Structure
• Proteins: Three-Dimensional Structure
• Protein Function: Myoglobin and Hemoglobin, Muscle Contraction, and Antibodies
  • Calmodulin_in_motion
• Carbohydrates
• Lipids and Biological Membranes
• Membrane Transport
  • A Physical Model of the β2-Adrenergic Receptor

ENZYMESENZYMES

• Enzymatic Catalysis
  • Aconitase
  • Serine Hydrolases
    • Acetylcholinesterase (AChE)
      • Acetylcholine
      • Flexibility_of_aromatic_residues_in_acetylcholinesterase
      • AChE inhibitors and substrates
        • 1eve AChE-Aricept complex
        • AChE_bivalent_inhibitors
  • Triose_Phosphate_Isomerase
• Enzyme Kinetics, Inhibition, and Control
• Biochemical Signaling

METABOLISMMETABOLISM

• Introduction to Metabolism
• Glucose Catabolism
• Glycogen Metabolism and Gluconeogenesis
• Citric Acid Cycle
• Electron Transport and Oxidative Phosphorylation
• Photosynthesis
• Lipid Metabolism
• Amino Acid Metabolism
• Mammalian Fuel Metabolism: Integration and Regulation

GENE EXPRESSION AND REPLICATIONGENE EXPRESSION AND REPLICATION

• Nucleotide Metabolism
• Nucleic Acid Structure
• DNA Replication, Repair, and Recombination
• Transcription and RNA Processing
• Protein Synthesis
• Regulation of Gene Expression

METHODS OF STRUCTURE DETERMINATIONMETHODS OF STRUCTURE DETERMINATION

• X-ray
  • X-ray_crystallography
    • Asymmetric_Unit
    • Biological_Unit
  • SAXS
• NMR
• Electron Microscopy

METHODS OF STRUCTURE & SEQUENCE ANALYSISMETHODS OF STRUCTURE & SEQUENCE ANALYSIS

• STRUCTURAL ANALYSIS & VISUALIZATION
  • Chime
  • User:Wayne Decatur/Teaching Proteopedia
  • User:Wayne Decatur/Homology Modeling
  • User:Wayne Decatur/Generate Unfolded Structures
• SEQUENCE ANALYSIS
  • User:Wayne Decatur/Sequence analysis tools