Kwon sandbox

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spinqualitylabelsall models PDB ID 3cin Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
3cin, resolution 1.70Å ()
Ligands:	, ,
Gene:	TM1419, TM_1419 (Thermotoga maritima MSB8)
Activity:	Inositol-3-phosphate synthase, with EC number 5.5.1.4
Structural annotation: Resources: CATH : 3Cina01, 3Cina02 InterPro : Ipr016040, Ipr013021, Ipr002587 Pfam : PF07994
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum, TOPSAN
Coordinates:	save as pdb, mmCIF, xml

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IntroductionIntroduction

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The c-Myc is a protonocogene, has the potential of becoming an oncogene if it under went specific mutations. This protein has been found to be mutated in Burkitt's lymphoma cell lines. The c-Myc protein is a transcription factor that regulates the expression of cell proliferation proteins. This protein is normally short lived, but when it has a point mutation that causes Thr58, it has been shown to have a much longer turnover rate.