3gpt: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3gpt.jpg|left|200px]]


The entry 3gpt is ON HOLD until Paper Publication
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{{STRUCTURE_3gpt|  PDB=3gpt  |  SCENE=  }}


Authors: Groll, M., Macherla, V.R., Manam, R.R., Arthur, K.A.M., Potts, C.B.
===Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: slow substrate ligand===


Description: Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: slow substrate ligand


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{{ABSTRACT_PUBMED_19678642}}
 
==About this Structure==
3GPT is a 28 chains structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GPT OCA].
 
==Reference==
<ref group="xtra">PMID:19678642</ref><references group="xtra"/>
[[Category: Proteasome endopeptidase complex]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Arthur, K A.M.]]
[[Category: Groll, M.]]
[[Category: Macherla, V R.]]
[[Category: Manam, R R.]]
[[Category: Potts, C B.]]
[[Category: Cancer therapy]]
[[Category: Cytoplasm]]
[[Category: Hydrolase]]
[[Category: Immunology]]
[[Category: Inhibitor]]
[[Category: Isopeptide bond]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Protease]]
[[Category: Proteasome]]
[[Category: Threonine protease]]
[[Category: Time dependent leaving group elimination]]
[[Category: Ubiquitin]]
[[Category: Ubl conjugation]]
[[Category: Zymogen]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 16 09:01:45 2009''

Revision as of 09:01, 16 September 2009

File:3gpt.jpg

Template:STRUCTURE 3gpt

Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: slow substrate ligandCrystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: slow substrate ligand

Template:ABSTRACT PUBMED 19678642

About this StructureAbout this Structure

3GPT is a 28 chains structure of sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Groll M, McArthur KA, Macherla VR, Manam RR, Potts BC. Snapshots of the fluorosalinosporamide/20S complex offer mechanistic insights for fine tuning proteasome inhibition. J Med Chem. 2009 Sep 10;52(17):5420-8. PMID:19678642 doi:10.1021/jm900559x

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