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User:Adithya Sagar/Sandbox DNA: Difference between revisions

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==Forms of DNA==
==Forms of DNA==
''See Also: [[Z-DNA]]''
''See Also: [[Z-DNA]]''
<applet load='A-DNA.pdb' name='A' size='350' frame='true' align='right' caption='A-DNA' align='left' scene='User:Adithya_Sagar/Sandbox_DNA/A-dna/1'/>
<applet load='B-DNA.pdb' name='B' size='350' frame='true' align='right' caption='B-DNA' align='left' scene='User:Adithya_Sagar/Sandbox_DNA/B-dna/3'/>
<applet load='Z-DNA.pdb' name='Z' size='350' frame='true' align='right' caption='Z-DNA' align='left' scene='User:Adithya_Sagar/Sandbox_DNA/Z-dna/1'/>
<jmol>
  <jmolCheckbox>
    <target>A</target>
    <scriptWhenChecked>sync jmolAppletB,jmolAppletZ</scriptWhenChecked>
    <scriptWhenUnchecked> sync OFF</scriptWhenUnchecked>
    <text> Synchronize</text>
</jmolCheckbox>
</jmol>


DNA is a very flexible molecule and has the ability to exist in various forms based on the environmental conditions.  Naturally occurring DNA double helices are classified into A, B and Z-types. A and B-forms of DNA are the right handed forms whereas [[Z-DNA]] is the left handed form. When hydrated the DNA generally assumes B-form. The A conformation is found when there is little water to interact with the helix. The formation of Z-DNA occurs with the methylation of  deoxycytosine residues and also during transcription where negative supercoiling stabilizes it.
DNA is a very flexible molecule and has the ability to exist in various forms based on the environmental conditions.  Naturally occurring DNA double helices are classified into A, B and Z-types. A and B-forms of DNA are the right handed forms whereas [[Z-DNA]] is the left handed form. When hydrated the DNA generally assumes B-form. The A conformation is found when there is little water to interact with the helix. The formation of Z-DNA occurs with the methylation of  deoxycytosine residues and also during transcription where negative supercoiling stabilizes it.
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