User:Adithya Sagar/Sandbox DNA: Difference between revisions
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''See Also: [[Z-DNA]]'' | ''See Also: [[Z-DNA]]'' | ||
<applet load='A-DNA.pdb' size=' | <applet load='A-DNA.pdb' size='350' frame='true' align='right' caption='Insert caption here' /> | ||
<applet load='B-DNA.pdb' size=' | <applet load='B-DNA.pdb' size='350' frame='true' align='right' caption='Insert caption here' /> | ||
<applet load='Z-DNA.pdb' size=' | <applet load='Z-DNA.pdb' size='350' frame='true' align='right' caption='Insert caption here' /> | ||
DNA is a very flexible molecule and has the ability to exist in various forms based on the environmental conditions. Naturally occurring DNA double helices are classified into A, B and Z-types. A and B-forms of DNA are the right handed forms whereas [[Z-DNA]] is the left handed form. When hydrated the DNA generally assumes B-form. The A conformation is found when there is little water to interact with the helix. The formation of Z-DNA occurs with the methylation of deoxycytosine residues and also during transcription where negative supercoiling stabilizes it. | DNA is a very flexible molecule and has the ability to exist in various forms based on the environmental conditions. Naturally occurring DNA double helices are classified into A, B and Z-types. A and B-forms of DNA are the right handed forms whereas [[Z-DNA]] is the left handed form. When hydrated the DNA generally assumes B-form. The A conformation is found when there is little water to interact with the helix. The formation of Z-DNA occurs with the methylation of deoxycytosine residues and also during transcription where negative supercoiling stabilizes it. | ||