Avian Influenza Neuraminidase, Tamiflu and Relenza: Difference between revisions
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[[Image:3D_Influenza_virus.png|frame|Structure of an influenza virus <ref>[http://en.wikipedia.org/wiki/Image:3D_Influenza_virus.png Image of influenza virus structure] was obtained from Wikipedia.</ref>.]] | [[Image:3D_Influenza_virus.png|frame|Structure of an influenza virus <ref>[http://en.wikipedia.org/wiki/Image:3D_Influenza_virus.png Image of influenza virus structure] was obtained from Wikipedia.</ref>.]] | ||
The surfaces of influenza viruses include, among other molecules, two glycoproteins named '''hemagglutinin (H)''' and '''neuraminidase (N)''', coded for by the viral segmented RNA genome. Each of these molecules is required for successful infection and spread in a host animal. The hemagglutinin attaches influenza to sialic acid on the surfaces of cells, enabling them to enter and infect cells. After the virus has replicated, neuraminidase (also called sialidase) removes sialic acid from the cell, enabling the newly assembled virions to be released in order to spread and infect other cells. | The surfaces of influenza viruses include, among other molecules, two glycoproteins named '''hemagglutinin (H)''' and '''neuraminidase (N)''', coded for by the viral segmented RNA genome. Each of these molecules is required for successful infection and spread in a host animal. The hemagglutinin attaches influenza to [[sialic acid]] on the surfaces of cells, enabling them to enter and infect cells. After the virus has replicated, neuraminidase (also called sialidase) removes sialic acid from the cell, enabling the newly assembled virions to be released in order to spread and infect other cells. | ||
The hemagglutinin ('''H''') and neuraminidase ('''N''') of influenza A are classified into various numbered serotypes or subtypes, such as H1N1, H2N2, H3N2, H5N1, and so forth<ref name="fluwikipedia">[http://en.wikipedia.org/wiki/Influenza Influenza] at Wikipedia.</ref>. | The hemagglutinin ('''H''') and neuraminidase ('''N''') of influenza A are classified into various numbered serotypes or subtypes, such as H1N1, H2N2, H3N2, H5N1, and so forth<ref name="fluwikipedia">[http://en.wikipedia.org/wiki/Influenza Influenza] at Wikipedia.</ref>. | ||
For more about neuraminidase, including references for the points made in this paragraph, please see [http://en.wikipedia.org/wiki/Influenza Influenza at Wikipedia]. | For more about neuraminidase, including references for the points made in this paragraph, please see [http://en.wikipedia.org/wiki/Influenza Influenza at Wikipedia]. | ||