User:Tilman Schirmer/Sandbox 204: Difference between revisions
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Overview
Allosteric product binding site
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<br>Although not modified (e | <br>Although not modified (i.e. phosphorylated) at the active Asp (Asp70), the Rec domains mediate formation of <scene name='User:Tilman_Schirmer/Sandbox_204/Dimer/1'>dimeric </scene> WspR. Two dimers, in turn, are associated by head-to-head contact to a <scene name='User:Tilman_Schirmer/Sandbox_204/Tetramer/1'>tetramer</scene> of approximate 222 (D2) symmetry. | ||
Revision as of 19:15, 1 July 2009
WspR
OverviewOverview
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from Pseudomonas aeruginosa is a response regulator with an unorthodox catalytic, diguanylate cyclase, output domain. It is composed of a canonical CheY-like response regulator receiver domain () and a C-terminal domain that confers the catalytic activity with all canonical present.
Although not modified (i.e. phosphorylated) at the active Asp (Asp70), the Rec domains mediate formation of WspR. Two dimers, in turn, are associated by head-to-head contact to a of approximate 222 (D2) symmetry.
Allosteric product binding siteAllosteric product binding site
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There are two allosteric sites ( and ) that are cross-linked by (c-di-GMP)2 dimers in the molecule. For a close-up click (, , ).