1ql9: Difference between revisions

Revision as of 08:43, 3 June 2009

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File:1ql9.png

Template:STRUCTURE 1ql9

FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH RAT TRYPSIN MUTANT X99RTFACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH RAT TRYPSIN MUTANT X99RT

Template:ABSTRACT PUBMED 12527302

About this StructureAbout this Structure

1QL9 is a 1 chain structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}^{[xtra 2]}^{[xtra 3]}

↑ Reyda S, Sohn C, Klebe G, Rall K, Ullmann D, Jakubke HD, Stubbs MT. Reconstructing the binding site of factor Xa in trypsin reveals ligand-induced structural plasticity. J Mol Biol. 2003 Jan 31;325(5):963-77. PMID:12527302
↑ Renatus M, Bode W, Huber R, Sturzebecher J, Stubbs MT. Structural and functional analyses of benzamidine-based inhibitors in complex with trypsin: implications for the inhibition of factor Xa, tPA, and urokinase. J Med Chem. 1998 Dec 31;41(27):5445-56. PMID:9876114 doi:10.1021/jm981068g
↑ Stubbs MT, Huber R, Bode W. Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin. FEBS Lett. 1995 Nov 13;375(1-2):103-7. PMID:7498454

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OCA

[1] Reyda S, Sohn C, Klebe G, Rall K, Ullmann D, Jakubke HD, Stubbs MT. Reconstructing the binding site of factor Xa in trypsin reveals ligand-induced structural plasticity. J Mol Biol. 2003 Jan 31;325(5):963-77. PMID:12527302

[2] Renatus M, Bode W, Huber R, Sturzebecher J, Stubbs MT. Structural and functional analyses of benzamidine-based inhibitors in complex with trypsin: implications for the inhibition of factor Xa, tPA, and urokinase. J Med Chem. 1998 Dec 31;41(27):5445-56. PMID:9876114 doi:10.1021/jm981068g

[3] Stubbs MT, Huber R, Bode W. Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin. FEBS Lett. 1995 Nov 13;375(1-2):103-7. PMID:7498454

[xtra 1]

[xtra 2]

[xtra 3]

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 ==Reference==
-<ref group="xtra">PMID:12527302</ref><references group="xtra"/>
+<ref group="xtra">PMID:12527302</ref><ref group="xtra">PMID:9876114</ref><ref group="xtra">PMID:7498454</ref><references group="xtra"/>
 [[Category: Rattus norvegicus]]
 [[Category: Trypsin]]
 [[Category: Stubbs, M T.]]
 [[Category: Hydrolase]]
+[[Category: Serine protease]]
 [[Category: Serine proteinase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:22:59 2009''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun  3 08:43:09 2009''