Sandbox1988: Difference between revisions
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<scene name='Sandbox1988/Backbone/1'>backbone structure</scene>, we see that very little of the molecule disappears, showing us that the structure is fairly simple and not complex. We also can see that the | <scene name='Sandbox1988/Backbone/1'>backbone structure</scene>, we see that very little of the molecule disappears, showing us that the structure is fairly simple and not complex. We also can see that the | ||
<scene name='Sandbox1988/Charged_areas/1'>changed areas</scene> of the molecules is standard to that of normal proteins, where the charged areas are placed on the outer structure of the protein, where it can interact with water. | <scene name='Sandbox1988/Charged_areas/1'>changed areas</scene> of the molecules is standard to that of normal proteins, where the charged areas are placed on the outer structure of the protein, where it can interact with water. | ||
{{STRUCTURE_1upg | PDB=1upg | SCENE= }} | |||
The<scene name='Sandbox1988/Amino_structure/1'>amino structure</scene> shows that 1upg is mostly comprised of 4 different amino acids. | The<scene name='Sandbox1988/Amino_structure/1'>amino structure</scene> shows that 1upg is mostly comprised of 4 different amino acids. | ||
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This protein works by binding with TraR, a regulator, which in turn prevents it from binding to DNA. overall, TraR is also regulated by TarM, and the normal functions of 1upg without the addition of quorum-sensing involves regulated the transcription of DNA as well as being DNA dependent. With the addition of TraR, taking away it's ability to bind with DNA, allows us to use this as a tumor-inducing plasmids within the 1upg. | This protein works by binding with TraR, a regulator, which in turn prevents it from binding to DNA. overall, TraR is also regulated by TarM, and the normal functions of 1upg without the addition of quorum-sensing involves regulated the transcription of DNA as well as being DNA dependent. With the addition of TraR, taking away it's ability to bind with DNA, allows us to use this as a tumor-inducing plasmids within the 1upg. | ||
{{STRUCTURE_1upg | PDB=1upg | SCENE= }} | {{STRUCTURE_1upg | PDB=1upg | SCENE= }} | ||
References made to: http://proteopedia.org/wiki/index.php/1upg | |||
Revision as of 18:05, 22 May 2009
1upg1upg
This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks! In Professor Sun’s guest lecture, he discusses the usefulness of using quorum-sensing and the applications it has to determining cell density, diffusion and efficiency. 1upg is a system that is controlled by quorum-sensing, working to relocate plasmids containing tumor-inducers into the protein. By transferring these plasmids to 1upg, it allows the ‘bacteria to synchronize infection’ when the sensing cells have become involved. 1upg is comprised of a , and has a cluster of 3 within the protein. When a look is taken at the , we see that very little of the molecule disappears, showing us that the structure is fairly simple and not complex. We also can see that the of the molecules is standard to that of normal proteins, where the charged areas are placed on the outer structure of the protein, where it can interact with water.
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| 1upg, resolution 1.80Å () | |||||||||
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| Non-Standard Residues: | |||||||||
| Related: | 1us6 | ||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
The shows that 1upg is mostly comprised of 4 different amino acids.
This protein works by binding with TraR, a regulator, which in turn prevents it from binding to DNA. overall, TraR is also regulated by TarM, and the normal functions of 1upg without the addition of quorum-sensing involves regulated the transcription of DNA as well as being DNA dependent. With the addition of TraR, taking away it's ability to bind with DNA, allows us to use this as a tumor-inducing plasmids within the 1upg.
| |||||||||
| 1upg, resolution 1.80Å () | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Non-Standard Residues: | |||||||||
| Related: | 1us6 | ||||||||
| |||||||||
| |||||||||
| |||||||||
| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
References made to: http://proteopedia.org/wiki/index.php/1upg