3d5m: Difference between revisions

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'''Unreleased structure'''
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[[Image:3d5m.jpg|left|200px]]


The entry 3d5m is ON HOLD
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{{STRUCTURE_3d5m|  PDB=3d5m |  SCENE=  }}


Authors: Kim, S.H., Tran, M.T., Ruebsam, F., Xiang, A.X., Ayida, B., McGuire, H., Ellis, D., Blazel, J., Tran, C.V., Murphy, D.E., Webber, S.E., Zhou, Y., Shah, A.M., Tsan, M., Showalter, R.E., Patel, R., Gobbi, A., LeBrun, L.A., Bartkowski, D.M., Nolan, T.G., Nor
===Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor===


Description: Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Jul 11 13:05:08 2008''
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{{ABSTRACT_PUBMED_18554907}}
 
==About this Structure==
3D5M is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D5M OCA].
 
==Reference==
<ref group="xtra">PMID:18554907</ref><references group="xtra"/>
[[Category: RNA-directed RNA polymerase]]
[[Category: Viruses]]
[[Category: Han, Q.]]
[[Category: Kissinger, C R.]]
[[Category: Showalter, R E.]]
[[Category: Zhao, Q.]]
[[Category: Hydrolase]]
[[Category: Nucleotidyltransferase]]
[[Category: Protein-ligand complex]]
[[Category: Rna polymerase]]
[[Category: Rna replication]]
[[Category: Rna-binding]]
[[Category: Transcription]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 20 17:13:17 2009''

Revision as of 17:13, 20 May 2009

File:3d5m.jpg

Template:STRUCTURE 3d5m

Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitorCrystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor

Template:ABSTRACT PUBMED 18554907

About this StructureAbout this Structure

3D5M is a 2 chains structure of sequences from Viruses. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Kim SH, Tran MT, Ruebsam F, Xiang AX, Ayida B, McGuire H, Ellis D, Blazel J, Tran CV, Murphy DE, Webber SE, Zhou Y, Shah AM, Tsan M, Showalter RE, Patel R, Gobbi A, LeBrun LA, Bartkowski DM, Nolan TG, Norris DA, Sergeeva MV, Kirkovsky L, Zhao Q, Han Q, Kissinger CR. Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase. Bioorg Med Chem Lett. 2008 Jul 15;18(14):4181-5. Epub 2008 May 24. PMID:18554907 doi:10.1016/j.bmcl.2008.05.083

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