User:Susana Retamal/Sandbox1: Difference between revisions

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Rsp1275 is a member of the Fnr-Crp family of transcriptional regulators. Homologues of the Fnr protein from ''E. coli'' have been identified in a variety of taxonomically (1) diverse bacterial species. The bacterium ''Rhodobacter spheroides 2.4.1'' encodes 8 members of this family, however only 2 have known function. The modeling of 7 of them were successfully obtained using 3D-Jigsaw, all being very similar in structure to Crp (the only one with crystal structure solved). The DNA binding domain helix-turn-helix is located in the C-terminal, and the N-terminal part contains the allosteric effector domain. Rsp1275 has been linked with salt-tolerance in ''Rhodobacter spheroides''. Different genes coding for the Fnr-Crp proteins of unknown function have been cloned and a multicopy test was performed to evaluate these as potential regulators of NaCl-responsive genes.  
Rsp1275 is a member of the Fnr-Crp family of transcriptional regulators. Homologues of the Fnr protein from ''E. coli'' have been identified in a variety of taxonomically (1) diverse bacterial species. The bacterium ''Rhodobacter spheroides 2.4.1'' encodes 8 members of this family, however only 2 have known function. The modeling of 7 of them were successfully obtained using 3D-Jigsaw, all being very similar in structure to Crp (the only one with crystal structure solved). The DNA binding domain helix-turn-helix is located in the C-terminal, and the N-terminal part contains the allosteric effector domain. Rsp1275 has been linked with salt-tolerance in ''Rhodobacter spheroides''. Different genes coding for the Fnr-Crp proteins of unknown function have been cloned and a multicopy test was performed to evaluate these as potential regulators of NaCl-responsive genes.  
# Jmol state version 11.5.35  2008-04-29 08:46;
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Revision as of 10:47, 27 April 2009

Background InformationBackground Information

Rsp1275 is a member of the Fnr-Crp family of transcriptional regulators. Homologues of the Fnr protein from E. coli have been identified in a variety of taxonomically (1) diverse bacterial species. The bacterium Rhodobacter spheroides 2.4.1 encodes 8 members of this family, however only 2 have known function. The modeling of 7 of them were successfully obtained using 3D-Jigsaw, all being very similar in structure to Crp (the only one with crystal structure solved). The DNA binding domain helix-turn-helix is located in the C-terminal, and the N-terminal part contains the allosteric effector domain. Rsp1275 has been linked with salt-tolerance in Rhodobacter spheroides. Different genes coding for the Fnr-Crp proteins of unknown function have been cloned and a multicopy test was performed to evaluate these as potential regulators of NaCl-responsive genes.


  1. Jmol state version 11.5.35 2008-04-29 08:46;
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 load /*file*/"http://bip.weizmann.ac.il/LIGIM/fgij/20090427/UPL_4ce0f944185ebb4f14fa229bc8fc7748.pdb";

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 Spacefill 0.0;
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 slab 100;depth 0;
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function _setSelectionState(); 

 set hideNotSelected false;

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 initialize;
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 set antialiasDisplay false;
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 set antialiasImages true;

end function;

_setState;


Evidence of Fnr-Crp protein Involvement in Transcriptional Response to NaClEvidence of Fnr-Crp protein Involvement in Transcriptional Response to NaCl

Physico - Chemical parameters for Rsp1275Physico - Chemical parameters for Rsp1275

Number of amino acids: 249

Molecular weight: 28014.2

Theoretical pI: 6.10


Amino Acid Composition
Amino Acid Number present Percentage of total present
Ala (A) 15 8.8%
Arg (R) 10 10.4%
Asn (N) 6 2.4%
Asp (D) 10 4.8%
Cys (C) 1 1.2%
Gln (Q) 5 2.8%
Glu (E) 11 8.0%
Gly (G) 9 7.6%
His (H) 10 2.4%
Ile (I) 3 4.0%
Leu (L) 21 14.5%
Lys (K) 6 1.2%
Met (M) 6 2.4%
Phe (F) 2 4.0%
Pro (P) 8 5.2%
Ser (S) 7 4.4%
Thr (T) 13 6.4%
Trp (W) 2 2.0%
Tyr (Y) 6 0.4%
Val (V) 12 5.6%
Pyl (O) 0 0.%
Sec (U) 0 0.0%

Amino Acid Conservation ScoresAmino Acid Conservation Scores

- POS: The position of the AA in the SEQRES derived sequence. - SEQ: The SEQRES derived sequence in one letter code. - 3LATOM: The ATOM derived sequence in three letter code, including the AA's positions as they appear in the PDB file and the chain identifier. - SCORE: The normalized conservation scores. - COLOR: The color scale representing the conservation scores (9 - conserved, 1 - variable). - CONFIDENCE INTERVAL: When using the bayesian method for calculating rates, a confidence interval is assigned to each of the inferred evolutionary conservation scores. - CONFIDENCE INTERVAL COLORS: When using the bayesian method for calculating rates. The color scale representing the lower and upper bounds of the confidence interval. - MSA DATA: The number of aligned sequences having an amino acid (non-gapped) from the overall number of sequences at each position. - RESIDUE VARIETY: The residues variety at each position of the multiple sequence alignment. 

POS	 SEQ	    3LATOM	SCORE		COLOR	CONFIDENCE INTERVAL	CONFIDENCE INTERVAL COLORS	MSA DATA	RESIDUE VARIETY
   	    	        	(normalized)	        	               
  1	   P	    PRO47:	-1.063		  8*	-1.567,-0.697			    9,7			    3/19	P                 
  2	   G	    GLY48:	-0.916		  8	-1.417,-0.529			    9,7			   13/19	G,K               
  3	   V	    VAL49:	 1.226		  2	 0.404, 2.816			    4,1			   13/19	C,E,Q,R,V         
  4	   T	    THR50:	 1.816		  1	 0.790, 2.816			    3,1			   14/19	A,E,Q,T           
  5	   L	    LEU51:	 0.649		  3*	-0.136, 1.367			    5,1			   18/19	I,L,V             
  6	   L	    LEU52:	-0.142		  5	-0.697, 0.404			    7,4			   18/19	F,I,L,Y           
  7	   E	    GLU53:	 1.061		  2*	 0.108, 1.367			    5,1			   18/19	A,E,I,K,Q,S,W     
  8	   E	    GLU54:	 0.909		  2*	 0.108, 1.367			    5,1			   18/19	A,E,Q,S           
  9	   G	    GLY55:	-0.349		  6	-0.852, 0.108			    7,5			   18/19	D,E,G,P           
 10	   Q	    GLN56:	-0.600		  7	-0.998,-0.344			    8,6			   18/19	D,E,Q,S           
 11	   G	    GLY57:	 2.391		  1	 2.816, 2.816			    1,1			   18/19	E,G,I,K,L,P,S,T,V 
 12	   S	    SER58:	 0.521		  4*	-0.136, 1.367			    5,1			   18/19	A,L,M,N,S,T       
 13	   A	    ALA59:	 2.175		  1	 1.367, 2.816			    1,1			   18/19	A,D,K,N,R,S,T     
 14	   H	    HIS60:	-0.278		  6	-0.852, 0.108			    7,5			   18/19	F,H,K,S           
 15	   L	    LEU61:	 1.898		  1	 0.790, 2.816			    3,1			   18/19	C,F,I,L,V,Y       
 16	   F	    PHE62:	 0.468		  4	-0.136, 0.790			    5,3			   18/19	A,F,L,S,Y         
 17	   T	    THR63:	 0.156		  5*	-0.529, 0.790			    7,3			   18/19	A,N,Q,S,T,V       
 18	   V	    VAL64:	-0.901		  8	-1.277,-0.697			    9,7			   18/19	I,L,V             
 19	   L	    LEU65:	 0.975		  2*	 0.108, 1.367			    5,1			   18/19	A,I,L,M,R,S,V     
 20	   S	    SER66:	-0.045		  5	-0.697, 0.404			    7,4			   18/19	E,H,R,S,T         
 21	   G	    GLY67:	-1.418		  9	-1.755,-1.277			    9,9			   18/19	G                 
 22	   L	    LEU68:	 0.334		  4	-0.344, 0.790			    6,3			   18/19	A,I,K,L,T,V       
 23	   G	    GLY69:	 0.572		  3*	-0.136, 1.367			    5,1			   18/19	A,G,I,L,M,V       
 24	   I	    ILE70:	-0.318		  6	-0.852, 0.108			    7,5			   18/19	I,K,R,T           
 25	   R	    ARG71:	 0.405		  4	-0.344, 0.790			    6,3			   18/19	I,L,R,S,T         
 26	   S	    SER72:	-0.248		  6	-0.852, 0.108			    7,5			   18/19	C,S,T,Y           
 27	   T	    THR73:	-0.039		  5	-0.529, 0.404			    7,4			   18/19	K,Q,R,T           
 28	   M	    MET74:	-0.296		  6	-0.852, 0.108			    7,5			   19/19	I,L,M,T,V         
 29	   L	    LEU75:	-0.075		  5	-0.529, 0.404			    7,4			   19/19	A,L,M,S,T         
 30	   E	    GLU76:	 0.959		  2*	 0.108, 1.367			    5,1			   19/19	E,G,P,S,T         
 31	   N	    ASN77:	 0.131		  5	-0.344, 0.404			    6,4			   19/19	D,E,N,Q,S,T       
 32	   G	    GLY78:	-1.441		  9	-1.755,-1.277			    9,9			   19/19	G                 
 33	   R	    ARG79:	-0.815		  7	-1.139,-0.529			    8,7			   19/19	D,E,K,R           
 34	   R	    ARG80:	-0.887		  8	-1.277,-0.529			    9,7			   19/19	E,Q,R             
 35	   Q	    GLN81:	-1.577		  9	-1.755,-1.417			    9,9			   19/19	Q                 
 36	   V	    VAL82:	-0.767		  7	-1.139,-0.529			    8,7			   19/19	I,L,M,V           
 37	   I	    ILE83:	-0.369		  6	-0.852, 0.108			    7,5			   19/19	E,I,L,T,V         
 38	   N	    ASN84:	 0.834		  3*	 0.108, 1.367			    5,1			   19/19	A,G,N,R,S         
 39	   F	    PHE85:	-0.749		  7	-1.139,-0.344			    8,6			   19/19	F,L,V             
 40	   L	    LEU86:	 0.791		  3*	 0.108, 1.367			    5,1			   19/19	A,C,D,H,L,Q       
 41	   F	    PHE87:	-0.246		  6	-0.852, 0.108			    7,5			   19/19	F,G,L             
 42	   P	    PRO88:	-0.534		  7	-0.998,-0.136			    8,5			   19/19	A,P,V             
 43	   G	    GLY89:	-0.907		  8	-1.277,-0.697			    9,7			   19/19	G,P,S             
 44	   D	    ASP90:	-1.388		  9	-1.567,-1.277			    9,9			   19/19	D,E               
 45	   F	    PHE91:	 0.303		  4	-0.344, 0.790			    6,3			   19/19	A,F,L,M,V,Y       
 46	   I	    ILE92:	-0.023		  5	-0.697, 0.404			    7,4			   19/19	E,F,I,L,V         
 47	   G	    GLY93:	-1.441		  9	-1.755,-1.277			    9,9			   19/19	G                 
 48	   L	    LEU94:	 0.935		  2*	 0.108, 1.367			    5,1			   19/19	E,F,L,M,R,W       
 49	   Q	    GLN95:	 0.552		  3*	-0.136, 1.367			    5,1			   19/19	A,D,E,N,P,Q       
 50	   A	    ALA96:	-0.391		  6	-1.139, 0.108			    8,5			   13/19	A,G               
 51	   G	    GLY97:	 0.022		  5	-0.697, 0.404			    7,4			   13/19	G,I,L             
 52	   L	    LEU98:	 2.561		  1	 2.816, 2.816			    1,1			   19/19	A,F,G,H,L,M,P,S,T 
 53	   A	    ALA99:	 2.362		  1	 1.367, 2.816			    1,1			   19/19	A,G,N,Q,R,S,T,V   
 54	   G	   GLY100:	 2.565		  1	 2.816, 2.816			    1,1			   19/19	D,E,G,I,L,M,N,Q,R,S
 55	   E	   GLU101:	 1.976		  1	 1.367, 2.816			    1,1			   19/19	A,E,H,K,N,Q,R,S,T 
 56	   M	   MET102:	 0.254		  4	-0.344, 0.790			    6,3			   19/19	H,M,N,S,V,Y       
 57	   R	   ARG103:	 1.111		  2	 0.404, 1.367			    4,1			   19/19	A,N,P,Q,R,S,T,V   
 58	   H	   HIS104:	 0.562		  3*	-0.136, 1.367			    5,1			   19/19	F,G,H,L,N,S,Y     
 59	   S	   SER105:	-0.561		  7	-0.998,-0.136			    8,5			   19/19	D,F,S,Y           
 60	   V	   VAL106:	-1.054		  8	-1.417,-0.852			    9,7			   19/19	A,T,V             
 61	   E	   GLU107:	-0.753		  7	-1.139,-0.529			    8,7			   19/19	D,E,Q,T           
 62	   S	   SER108:	-1.062		  8	-1.417,-0.852			    9,7			   19/19	A,S,T             
 63	   T	   THR109:	-0.040		  5	-0.529, 0.404			    7,4			   19/19	A,I,L,T,V         
 64	   T	   THR110:	-0.845		  7	-1.277,-0.529			    9,7			   19/19	E,G,S,T           
 65	   T	   THR111:	 0.081		  5*	-0.529, 0.790			    7,3			   19/19	A,D,E,G,T         
 66	   M	   MET112:	 0.816		  3*	 0.108, 1.367			    5,1			   19/19	A,C,L,M,S,T,V     
 67	   V	   VAL113:	 0.008		  5	-0.529, 0.404			    7,4			   19/19	E,L,M,R,T,V       
 68	   L	   LEU114:	-0.103		  5	-0.697, 0.404			    7,4			   19/19	I,L,M,V           
 69	   C	   CYS115:	-0.836		  7	-1.277,-0.529			    9,7			   19/19	A,C,V             
 70	   V	   VAL116:	 2.036		  1	 1.367, 2.816			    1,1			   19/19	C,E,I,K,Q,R,T,V   
 71	   F	   PHE117:	-0.769		  7	-1.277,-0.344			    9,6			   19/19	F,I,V             
 72	   N	   ASN118:	 1.494		  1	 0.790, 2.816			    3,1			   19/19	A,F,G,K,N,P,R,S   
 73	   R	   ARG119:	-0.223		  6	-0.697, 0.108			    7,5			   19/19	A,F,K,R,Y         
 74	   A	   ALA120:	 1.689		  1	 0.790, 2.816			    3,1			   18/19	A,D,E,G,K,N,S,T   
 75	   D	   ASP121:	 1.492		  1	 0.790, 2.816			    3,1			   18/19	D,I,L,P,T,V       
 76	   L	   LEU122:	-0.309		  6	-0.852, 0.108			    7,5			   18/19	F,L               
 77	   W	   TRP123:	 1.635		  1	 0.790, 2.816			    3,1			   18/19	D,E,F,G,L,Q,W     
 78	   D	   ASP124:	 0.991		  2*	 0.108, 1.367			    5,1			   18/19	A,D,E,Q,R         
 79	   L	   LEU125:	-0.503		  6	-0.998,-0.136			    8,5			   18/19	F,L,M,R           
 80	   F	   PHE126:	 0.962		  2*	 0.108, 1.367			    5,1			   18/19	A,F,I,L,M,S       
 81	   R	   ARG127:	 1.061		  2*	 0.108, 1.367			    5,1			   19/19	E,G,L,Q,R,S       
 82	   E	   GLU128:	 0.612		  3*	-0.136, 1.367			    5,1			   19/19	E,K,N,S,T         
 83	   E	   GLU129:	 0.413		  4	-0.344, 0.790			    6,3			   19/19	D,E,M,Q,R,T       
 84	   P	   PRO130:	-1.243		  9	-1.567,-0.998			    9,8			   19/19	P,Q               
 85	   E	   GLU131:	-0.080		  5	-0.697, 0.404			    7,4			   19/19	E,H,K,N,Q         
 86	   R	   ARG132:	 0.801		  3*	 0.108, 1.367			    5,1			   19/19	I,L,M,R,V         
 87	   A	   ALA133:	 0.460		  4	-0.344, 0.790			    6,3			   19/19	A,G,L,Q,R,S       
 88	   Y	   TYR134:	 0.879		  2*	 0.108, 1.367			    5,1			   19/19	C,H,L,Q,R,Y       
 89	   D	   ASP135:	 0.376		  4	-0.344, 0.790			    6,3			   19/19	A,D,E,Q,R,S       
 90	   L	   LEU136:	-0.372		  6	-0.852, 0.108			    7,5			   19/19	I,L,M             
 91	   T	   THR137:	 0.789		  3*	 0.108, 1.367			    5,1			   19/19	H,L,M,N,T,W       
 92	   W	   TRP138:	 0.918		  2*	 0.108, 1.367			    5,1			   19/19	A,D,E,R,T,W       
 93	   I	   ILE139:	 0.435		  4	-0.344, 0.790			    6,3			   19/19	E,F,I,L,M,Q       
 94	   A	   ALA140:	-0.562		  7	-0.998,-0.136			    8,5			   19/19	A,M,N,S,T         
 95	   A	   ALA141:	 0.604		  3*	-0.136, 1.367			    5,1			   19/19	A,F,I,L,S,T       
 96	   V	   VAL142:	 1.537		  1	 0.790, 2.816			    3,1			   19/19	A,D,G,K,N,R,S,T,V 
 97	   E	   GLU143:	-1.054		  8	-1.417,-0.852			    9,7			   19/19	E,G,K             
 98	   E	   GLU144:	-0.200		  6	-0.697, 0.108			    7,5			   19/19	E,I,L,M           
 99	   H	   HIS145:	 0.536		  3*	-0.136, 1.367			    5,1			   19/19	A,D,H,K,M,Q,S     
100	   F	   PHE146:	 1.103		  2*	 0.108, 2.816			    5,1			   19/19	A,F,G,L,N,Q,R,S   
101	   L	   LEU147:	-0.661		  7	-1.139,-0.344			    8,6			   19/19	A,D,L             
102	   G	   GLY148:	-0.441		  6	-0.852,-0.136			    7,5			   19/19	E,G,Q,R           
103	   E	   GLU149:	-0.539		  7	-0.998,-0.136			    8,5			   19/19	D,E,K,Q           
104	   T	   THR150:	 0.063		  5	-0.529, 0.404			    7,4			   19/19	H,M,Q,T,W         
105	   I	   ILE151:	-0.555		  7	-0.998,-0.136			    8,5			   19/19	A,I,L,M           
106	   A	   ALA152:	-0.041		  5	-0.697, 0.404			    7,4			   19/19	A,G,L,V           
107	   S	   SER153:	 0.364		  4	-0.344, 0.790			    6,3			   19/19	L,S,T,V,Y         
108	   L	   LEU154:	-1.173		  8	-1.567,-0.998			    9,8			   19/19	I,L               
109	   G	   GLY155:	-1.243		  9	-1.567,-0.998			    9,8			   19/19	G,S               
110	   Q	   GLN156:	-0.805		  7	-1.139,-0.529			    8,7			   19/19	K,N,Q,R           
111	   R	   ARG157:	 0.138		  5	-0.344, 0.404			    6,4			   19/19	D,K,M,Q,R         
112	   D	   ASP158:	-0.224		  6	-0.697, 0.108			    7,5			   19/19	C,D,N,S,T         
113	   A	   ALA159:	-1.362		  9	-1.567,-1.139			    9,8			   19/19	A,I               
114	   T	   THR160:	 0.916		  2*	 0.108, 1.367			    5,1			   19/19	D,E,N,Q,R,T,V     
115	   E	   GLU161:	-1.294		  9	-1.567,-1.139			    9,8			   19/19	E,V               
116	   R	   ARG162:	-0.855		  7	-1.277,-0.529			    9,7			   19/19	K,R               
117	   L	   LEU163:	-0.418		  6	-0.852,-0.136			    7,5			   19/19	I,L,V             
118	   A	   ALA164:	-1.261		  9	-1.567,-1.139			    9,8			   19/19	A,G,T             
119	   W	   TRP165:	-0.387		  6	-0.852,-0.136			    7,5			   19/19	A,H,S,W           
120	   A	   ALA166:	-0.327		  6	-0.852, 0.108			    7,5			   19/19	A,F,L,Y           
121	   L	   LEU167:	-0.623		  7	-1.139,-0.344			    8,6			   19/19	I,L               
122	   L	   LEU168:	 2.061		  1	 1.367, 2.816			    1,1			   19/19	A,H,L,S,V,Y       
123	   R	   ARG169:	 0.245		  4	-0.344, 0.790			    6,3			   19/19	D,G,I,L,N,R       
124	   I	   ILE170:	-0.525		  6	-0.998,-0.136			    8,5			   19/19	I,L,W             
125	   H	   HIS171:	 0.296		  4	-0.344, 0.790			    6,3			   19/19	A,C,H,R,S         
126	   E	   GLU172:	 2.674		  1	 2.816, 2.816			    1,1			   19/19	C,D,E,H,K,N,Q,R,T 
127	   R	   ARG173:	-1.085		  8	-1.417,-0.852			    9,7			   19/19	A,H,R             
128	   L	   LEU174:	 1.821		  1	 0.790, 2.816			    3,1			   19/19	A,D,F,L,Q,S,Y     
129	   S	   SER175:	 1.545		  1	 0.790, 2.816			    3,1			   19/19	A,E,G,L,S         
130	   A	   ALA176:	 0.878		  2*	-0.136, 1.367			    5,1			   19/19	A,G,N,P,Q,R,T     
131	   I	   ILE177:	 1.408		  1	 0.404, 2.816			    4,1			   17/19	E,I,K,P,Q,R,T     
132	   G	   GLY178:	-0.288		  6	-0.852, 0.108			    7,5			   17/19	G,N,S,T           
133	   L	   LEU179:	 0.548		  3*	-0.344, 1.367			    6,1			   17/19	A,F,L,N,V         
134	   A	   ALA180:	-0.547		  7	-0.998,-0.136			    8,5			   17/19	A,G,S,T           
135	   E	   GLU181:	 1.841		  1	 0.790, 2.816			    3,1			   18/19	A,D,E,G,H,K,P,S   
136	   R	   ARG182:	 0.783		  3*	-0.136, 1.367			    5,1			   17/19	D,K,M,R,T,V       
137	   G	   GLY183:	 0.172		  5*	-0.697, 0.790			    7,3			    2/19	G,T               
138	   R	   ARG184:	 0.226		  4*	-0.529, 0.790			    7,3			   19/19	A,E,Q,R,T         
139	   V	   VAL185:	-0.496		  6	-1.139,-0.136			    8,5			   19/19	F,L,V             
140	   P	   PRO186:	 0.687		  3*	-0.136, 1.367			    5,1			   19/19	D,P,R,S,T         
141	   M	   MET187:	-0.889		  8	-1.277,-0.529			    9,7			   19/19	L,M,V             
142	   P	   PRO188:	-0.993		  8	-1.417,-0.697			    9,7			   19/19	A,P,T             
143	   W	   TRP189:	-1.104		  8	-1.417,-0.852			    9,7			   19/19	L,M,W             
144	   R	   ARG190:	-0.591		  7	-0.998,-0.344			    8,6			   19/19	A,G,R,S,T         
145	   Q	   GLN191:	-1.107		  8	-1.417,-0.852			    9,7			   19/19	Q,R,W             
146	   Q	   GLN192:	-0.300		  6	-0.852, 0.108			    7,5			   19/19	A,E,G,Q,T         
147	   D	   ASP193:	-0.990		  8	-1.277,-0.697			    9,7			   19/19	D,E,Q             
148	   L	   LEU194:	-0.925		  8	-1.277,-0.697			    9,7			   19/19	I,L,M             
149	   A	   ALA195:	-1.427		  9	-1.755,-1.277			    9,9			   19/19	A,G               
150	   D	   ASP196:	-1.403		  9	-1.567,-1.277			    9,9			   19/19	D,N               
151	   A	   ALA197:	 0.072		  5	-0.529, 0.404			    7,4			   19/19	A,F,Y             
152	   L	   LEU198:	-1.443		  9	-1.755,-1.277			    9,9			   19/19	L                 
153	   G	   GLY199:	-1.441		  9	-1.755,-1.277			    9,9			   19/19	G                 
154	   L	   LEU200:	-1.044		  8	-1.417,-0.697			    9,7			   19/19	L,T               
155	   S	   SER201:	-1.493		  9	-1.755,-1.417			    9,9			   19/19	S,T               
156	   L	   LEU202:	-0.226		  6	-0.697, 0.108			    7,5			   19/19	I,L,P,V           
157	   V	   VAL203:	-1.296		  9	-1.567,-1.139			    9,8			   19/19	E,V               
158	   H	   HIS204:	-1.435		  9	-1.755,-1.277			    9,9			   19/19	H,T               
159	   T	   THR205:	-1.190		  8	-1.417,-0.998			    9,8			   19/19	I,T,V             
160	   N	   ASN206:	-1.519		  9	-1.755,-1.417			    9,9			   19/19	N,S               
161	   K	   LYS207:	-1.390		  9	-1.567,-1.277			    9,9			   19/19	K,R               
162	   T	   THR208:	-0.802		  7	-1.277,-0.529			    9,7			   19/19	L,Q,T,V           
163	   I	   ILE209:	 0.127		  5*	-0.529, 0.790			    7,3			   19/19	F,I,L,M,V         
164	   R	   ARG210:	-0.459		  6	-0.852,-0.136			    7,5			   19/19	G,K,R,S,T         
165	   R	   ARG211:	-0.501		  6	-0.998,-0.136			    8,5			   19/19	A,K,R,Y           
166	   L	   LEU212:	-0.866		  7	-1.277,-0.529			    9,7			   19/19	F,L               
167	   R	   ARG213:	 0.305		  4	-0.344, 0.790			    6,3			   18/19	A,E,K,Q,R         
168	   E	   GLU214:	-0.134		  5	-0.697, 0.404			    7,4			   18/19	E,K,R             
169	   T	   THR215:	 1.641		  1	 0.790, 2.816			    3,1			   16/19	D,H,I,L,M,Q,S,T   
170	   G	   GLY216:	-1.323		  9	-1.755,-1.139			    9,8			   14/19	G                 
171	   H	   HIS217:	 0.687		  3*	-0.136, 1.367			    5,1			    4/19	A,H,M,V           
172	   A	   ALA218:	-0.749		  7*	-1.277,-0.344			    9,6			    4/19	A,I               
173	   L	   LEU219:	-0.200		  6*	-0.852, 0.404			    7,4			    4/19	A,L,T             
174	   W	   TRP220:	 0.478		  4*	-0.344, 1.367			    6,1			    4/19	I,L,V,W           
175	   E	   GLU221:	 0.163		  5*	-0.697, 0.790			    7,3			    4/19	E,I,Q             
176	   G	   GLY222:	-0.526		  7*	-1.139,-0.136			    8,5			    4/19	G,H               
177	   G	   GLY223:	-0.842		  7*	-1.417,-0.529			    9,7			    2/19	G                 
178	   T	   THR224:	 0.181		  4*	-0.697, 0.790			    7,3			    2/19	G,T               
179	   L	   LEU225:	-0.327		  6*	-1.139, 0.404			    8,4			    1/19	L                 
180	   F	   PHE226:	-0.327		  6*	-1.139, 0.404			    8,4			    1/19	F                 
181	   V	   VAL227:	-0.327		  6*	-1.139, 0.404			    8,4			    1/19	V




Structure of the Proposed rsp1275'

3D Image of proposed rsp1275 protein

Drag the structure with the mouse to rotate
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