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=Background Information= | =Background Information= | ||
Rsp1275 is a member of the Fnr-Crp family of transcriptional regulators. Homologues of the Fnr protein from ''E. coli'' have been identified in a variety of taxonomically (1) diverse bacterial species. | |||
The bacterium ''Rhodobacter spheroides 2.4.1'' encodes 8 members of this family, however only 2 have known function. The modeling of 7 of them were successfully obtained using 3D-Jigsaw, all | |||
being very similar in structure to Crp (the only one with crystal structure solved). The DNA binding domain helix-turn-helix is located in the C-terminal, and the N-terminal part contains the | |||
allosteric effector domain. | |||
=Evidence of Fnr-Crp protein Involvement in Transcriptional Response to NaCl= | =Evidence of Fnr-Crp protein Involvement in Transcriptional Response to NaCl= | ||