Rebecca Martin/Sandbox1: Difference between revisions

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<scene name='Rebecca_Martin/Sandbox1/Dimeric_iga_1/1'>dimeric iga</scene>
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== Introduction ==
== Introduction ==
{{STRUCTURE_3cm9 |  PDB=3cm9  |  SCENE=  IgA1}}
{{STRUCTURE_3cm9 |  PDB=3cm9  |  SCENE=  IgA1}}
<applet load='1iga' size='300' frame='true' align='right' caption='IgA1.' />


== General Structure ==
== General Structure ==


== Dimeric and Secretory IgA ==
== Dimeric and Secretory IgA ==
<scene name='Rebecca_Martin/Sandbox1/Dimeric_iga_1/1'>dimeric iga</scene>


== Secretory Component and Polyimmunoglobulin receptor ==
== Secretory Component and Polyimmunoglobulin receptor ==

Revision as of 16:43, 22 April 2009

IntroductionIntroduction

Template:STRUCTURE 3cm9

IgA1.

Drag the structure with the mouse to rotate

General StructureGeneral Structure

Dimeric and Secretory IgADimeric and Secretory IgA

Secretory Component and Polyimmunoglobulin receptorSecretory Component and Polyimmunoglobulin receptor

This is the secretory component.

Drag the structure with the mouse to rotate


Insights into FunctionInsights into Function

EvolutionEvolution

Implications in Science and MedicineImplications in Science and Medicine

Limitations of the Current StudiesLimitations of the Current Studies

Questions for the FutureQuestions for the Future

LinksLinks

IgAIgA

  • Model of human IgA1 determined by solution scattering, curve-fitting, and homology modeling 1iga
  • Model of human IgA2 determined by solution scattering, curve fitting and homology modelling 1r70
  • Crystal structure of human FcaRI bound to IgA1-Fc 1ow0
  • Solution structure of human dimeric immunoglobulin A 2qtj
  • Solution structure of human secretory IgA1 3chn
  • Solution Structure of Human SIgA2 3cm9
  • Solution structure of human secretory component 2ocw

ReceptorsReceptors

  • Crystal Structure of a Ligand-Binding Domain of the Human Polymeric Ig Receptor, pIgR 1XED
  • Crystal structure of human FcaRI 10vz
  • Crystal structure of a Staphylococcus aureus protein (SSL7) in complex with Fc of human IgA1 2qej

For ComparisonFor Comparison

  • IgM: Solution structure of human Immunoglobulin M 2rcj
  • IgG:
  • IgD:
  • IgE:


ReferencesReferences

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Rebecca Martin, Jaime Prilusky