3cvk: Difference between revisions

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'''Unreleased structure'''
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[[Image:3cvk.jpg|left|200px]]


The entry 3cvk is ON HOLD until Apr 18 2010
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{{STRUCTURE_3cvk|  PDB=3cvk  |  SCENE=  }}


Authors: Zhao, Q., Showalter, R.E., Han, Q., Kissinger, C.R.
===Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor===


Description: Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor


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{{ABSTRACT_PUBMED_18722768}}
 
==About this Structure==
3CVK is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CVK OCA].
 
==Reference==
<ref group="xtra">PMID:18722768</ref><references group="xtra"/>
[[Category: Polyribonucleotide nucleotidyltransferase]]
[[Category: Viruses]]
[[Category: Han, Q.]]
[[Category: Kissinger, C R.]]
[[Category: Showalter, R E.]]
[[Category: Zhao, Q.]]
[[Category: Nucleotide-binding]]
[[Category: Nucleotidyltransferase]]
[[Category: Protein-ligand complex]]
[[Category: Rna-directed rna polymerase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 22 11:25:59 2009''

Revision as of 11:26, 22 April 2009

File:3cvk.jpg

Template:STRUCTURE 3cvk

Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitorCrystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor

Template:ABSTRACT PUBMED 18722768

About this StructureAbout this Structure

3CVK is a 2 chains structure of sequences from Viruses. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Ruebsam F, Sun Z, Ayida BK, Webber SE, Zhou Y, Zhao Q, Kissinger CR, Showalter RE, Shah AM, Tsan M, Patel R, Lebrun LA, Kamran R, Sergeeva MV, Bartkowski DM, Nolan TG, Norris DA, Kirkovsky L. Hexahydro-pyrrolo- and hexahydro-1H-pyrido[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5002-5. Epub 2008 Aug 9. PMID:18722768 doi:10.1016/j.bmcl.2008.08.017

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