2w3i: Difference between revisions

Revision as of 12:18, 9 April 2009

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File:2w3i.jpg

Template:STRUCTURE 2w3i

CRYSTAL STRUCTURE OF FXA IN COMPLEX WITH 4,4-DISUBSTITUTED PYRROLIDINE-1,2-DICARBOXAMIDE INHIBITOR 2CRYSTAL STRUCTURE OF FXA IN COMPLEX WITH 4,4-DISUBSTITUTED PYRROLIDINE-1,2-DICARBOXAMIDE INHIBITOR 2

Template:ABSTRACT PUBMED 19231206

About this StructureAbout this Structure

2W3I is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Van Huis CA, Casimiro-Garcia A, Bigge CF, Cody WL, Dudley DA, Filipski KJ, Heemstra RJ, Kohrt JT, Leadley RJ Jr, Narasimhan LS, McClanahan T, Mochalkin I, Pamment M, Peterson JT, Sahasrabudhe V, Schaum RP, Edmunds JJ. Exploration of 4,4-disubstituted pyrrolidine-1,2-dicarboxamides as potent, orally active Factor Xa inhibitors with extended duration of action. Bioorg Med Chem. 2009 Mar 15;17(6):2501-11. Epub 2009 Feb 3. PMID:19231206 doi:10.1016/j.bmc.2009.01.063

Page seeded by OCA on Thu Apr 9 12:18:33 2009

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Van Huis CA, Casimiro-Garcia A, Bigge CF, Cody WL, Dudley DA, Filipski KJ, Heemstra RJ, Kohrt JT, Leadley RJ Jr, Narasimhan LS, McClanahan T, Mochalkin I, Pamment M, Peterson JT, Sahasrabudhe V, Schaum RP, Edmunds JJ. Exploration of 4,4-disubstituted pyrrolidine-1,2-dicarboxamides as potent, orally active Factor Xa inhibitors with extended duration of action. Bioorg Med Chem. 2009 Mar 15;17(6):2501-11. Epub 2009 Feb 3. PMID:19231206 doi:10.1016/j.bmc.2009.01.063

[xtra 1]

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-'''Unreleased structure'''
+{{Seed}}
+[[Image:2w3i.jpg|left|200px]]
-The entry 2w3i is ON HOLD
+<!--
+The line below this paragraph, containing "STRUCTURE_2w3i", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_2w3i|  PDB=2w3i  |  SCENE=  }}
-Authors: Zhang, E., Mochalkin, I., Casimiro-Garcia, A., Van Huis, C.
+===CRYSTAL STRUCTURE OF FXA IN COMPLEX WITH 4,4-DISUBSTITUTED PYRROLIDINE-1,2-DICARBOXAMIDE INHIBITOR 2===
-Description: Crystal Structure of FXa in complex with 4,4-disubstituted pyrrolidine-1,2-dicarboxamide inhibitor 2
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 20 07:35:30 2008''
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_19231206}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 19231206 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_19231206}}
+==About this Structure==
+W3I is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W3I OCA].
+==Reference==
+<ref group="xtra">PMID:19231206</ref><references group="xtra"/>
+[[Category: Coagulation factor Xa]]
+[[Category: Homo sapiens]]
+[[Category: Casimiro-Garcia, A.]]
+[[Category: Huis, C A.Van.]]
+[[Category: Mochalkin, I.]]
+[[Category: Zhang, E.]]
+[[Category: Blood clotting]]
+[[Category: Blood coagulation]]
+[[Category: Calcium]]
+[[Category: Cleavage on pair of basic residue]]
+[[Category: Drug design]]
+[[Category: Egf-like domain]]
+[[Category: Fxa coagulation factor inhibitor]]
+[[Category: Gamma-carboxyglutamic acid]]
+[[Category: Glycoprotein]]
+[[Category: Hydrolase]]
+[[Category: Hydroxylation]]
+[[Category: Polymorphism]]
+[[Category: Protease]]
+[[Category: Secreted]]
+[[Category: Serine protease]]
+[[Category: Zymogen]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr  9 12:18:33 2009''