3fqv: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3fqv.jpg|left|200px]]


The entry 3fqv is ON HOLD until Paper Publication
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{{STRUCTURE_3fqv|  PDB=3fqv  |  SCENE=  }}


Authors: Anderson, A.C., Frey, K.M., Liu, J., Lombardo, M.N.
===Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3-methoxy-4-phenylphenyl)but-1-ynyl]-6-methylpyrimidine===


Description: Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3-methoxy-4-phenylphenyl)but-1-ynyl]-6-methylpyrimidine


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{{ABSTRACT_PUBMED_19249312}}
 
==About this Structure==
3FQV is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_rf122 Staphylococcus aureus rf122]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FQV OCA].
 
==Reference==
<ref group="xtra">PMID:19249312</ref><references group="xtra"/>
[[Category: Dihydrofolate reductase]]
[[Category: Staphylococcus aureus rf122]]
[[Category: Anderson, A C.]]
[[Category: Frey, K M.]]
[[Category: Liu, J.]]
[[Category: Lombardo, M N.]]
[[Category: Oxidoreductase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 25 12:33:15 2009''

Revision as of 13:33, 25 March 2009

File:3fqv.jpg

Template:STRUCTURE 3fqv

Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3-methoxy-4-phenylphenyl)but-1-ynyl]-6-methylpyrimidineStaphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3-methoxy-4-phenylphenyl)but-1-ynyl]-6-methylpyrimidine

Template:ABSTRACT PUBMED 19249312

About this StructureAbout this Structure

3FQV is a 1 chain structure of sequence from Staphylococcus aureus rf122. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Frey KM, Liu J, Lombardo MN, Bolstad DB, Wright DL, Anderson AC. Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance. J Mol Biol. 2009 Apr 17;387(5):1298-308. Epub 2009 Feb 26. PMID:19249312 doi:10.1016/j.jmb.2009.02.045

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