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===Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8=== | ===Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8=== | ||
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{{ABSTRACT_PUBMED_18275813}} | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
3B2V is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B2V OCA]. | 3B2V is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B2V OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:18275813</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
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[[Category: Ubl conjugation]] | [[Category: Ubl conjugation]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 22 10:49:49 2009'' | ||
Revision as of 11:49, 22 March 2009
Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8
Template:ABSTRACT PUBMED 18275813
DiseaseDisease
Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, susceptibility to OMIM:[131550]
About this StructureAbout this Structure
3B2V is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Li S, Kussie P, Ferguson KM. Structural basis for EGF receptor inhibition by the therapeutic antibody IMC-11F8. Structure. 2008 Feb;16(2):216-27. PMID:18275813 doi:10.1016/j.str.2007.11.009
Page seeded by OCA on Sun Mar 22 10:49:49 2009
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Pages with broken file links
- Homo sapiens
- Receptor protein-tyrosine kinase
- Ferguson, K M.
- Kussie, P.
- Li, S.
- Alternative splicing
- Anti-oncogene
- Antigen:antibody complex
- Antitumor
- Atp-binding
- Cell cycle
- Cell surface receptor
- Disease mutation
- Drug
- Fab fragment
- Glycoprotein
- Immune system/transferase complex
- Kinase
- Membrane
- Nucleotide-binding
- Phosphoprotein
- Polymorphism
- Secreted
- Transferase
- Transmembrane
- Tyrosine-protein kinase
- Ubl conjugation