Triose Phosphate Isomerase: Difference between revisions
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'''Triose Phosphate Isomerase''' | '''Triose Phosphate Isomerase''' | ||
{{STRUCTURE_1tim | PDB=1tim | SCENE= }} | |||
== Overview == | |||
(TPI or TIM) which catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate, an essential process in the glycolytic pathway. | |||
== Mechanism == | == Mechanism == | ||
TPI catalyzes the transfer of a hydrogen atom from carbon 1 to carbon 2, an intramolecular oxidation-reduction. This isomerization of a ketose to an aldose proceeds through an enediol intermediate.<Biochemistry 6th Edition> | |||
=== Acid Base Catalysis === | === Acid Base Catalysis === | ||
Revision as of 16:59, 19 March 2009
Triose Phosphate Isomerase
OverviewOverview
(TPI or TIM) which catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate, an essential process in the glycolytic pathway.
MechanismMechanism
TPI catalyzes the transfer of a hydrogen atom from carbon 1 to carbon 2, an intramolecular oxidation-reduction. This isomerization of a ketose to an aldose proceeds through an enediol intermediate.<Biochemistry 6th Edition>
Acid Base CatalysisAcid Base Catalysis
Diagram .<ref name= "web.virginia.edu" [1]