Sandbox315: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Revision as of 19:45, 4 March 2009 view source Student (talk \| contribs) students 33,697 edits No edit summary ← Older edit		Revision as of 19:45, 4 March 2009 view source Student (talk \| contribs) students 33,697 edits No edit summary Newer edit →
Line 4:		Line 4:
	==Macrophage Elastase==		==Macrophage Elastase==

	Macrophage elastase (MPP-12) is an enzyme mainly expressed in alveolar macrophages in homo sapiens. It gives rise to emphysema by degrading elastin and by deactivating alpha1-proteinase inhibitor (alpha1-PI). The crystal structure of the enzyme was determined by X-ray shows a <scene name='Sandbox315/1jk3_hydrophobic/1'>hydrophobic</scene> active-site cleft. The red structures indicate where the hydrophobic residues are located. The enzyme has ~~one~~ <scene name='Sandbox315/Beta_sheet/1'>~~Beta Sheet~~</scene> ~~highlighted~~ in purple.		Macrophage elastase (MPP-12) is an enzyme mainly expressed in alveolar macrophages in homo sapiens. It gives rise to emphysema by degrading elastin and by deactivating alpha1-proteinase inhibitor (alpha1-PI). The crystal structure of the enzyme was determined by X-ray shows a <scene name='Sandbox315/1jk3_hydrophobic/1'>hydrophobic</scene> active-site cleft. The red structures indicate where the hydrophobic residues are located. The enzyme has two <scene name='Sandbox315/Beta_sheet/1'>beta sheets</scene> shown in purple.