3dpf: Difference between revisions

Revision as of 15:48, 4 March 2009

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File:3dpf.jpg

Template:STRUCTURE 3dpf

Crystal structure of the complex between MMP-8 and a non-zinc chelating inhibitorCrystal structure of the complex between MMP-8 and a non-zinc chelating inhibitor

Template:ABSTRACT PUBMED 19173605

About this StructureAbout this Structure

3DPF is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

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↑ Pochetti G, Montanari R, Gege C, Chevrier C, Taveras AG, Mazza F. Extra Binding Region Induced by Non-Zinc Chelating Inhibitors into the S(1)' Subsite of Matrix Metalloproteinase 8 (MMP-8) (dagger). J Med Chem. 2009 Jan 27. PMID:19173605 doi:http://dx.doi.org/10.1021/jm801166j
↑ Wasserman ZR. Making a new turn in matrix metalloprotease inhibition. Chem Biol. 2005 Feb;12(2):143-4. PMID:15734640 doi:http://dx.doi.org/10.1016/j.chembiol.2005.01.008
↑ Johnson AR, Pavlovsky AG, Ortwine DF, Prior F, Man CF, Bornemeier DA, Banotai CA, Mueller WT, McConnell P, Yan C, Baragi V, Lesch C, Roark WH, Wilson M, Datta K, Guzman R, Han HK, Dyer RD. Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects. J Biol Chem. 2007 Sep 21;282(38):27781-91. Epub 2007 Jul 10. PMID:17623656 doi:http://dx.doi.org/10.1074/jbc.M703286200
↑ Morales R, Perrier S, Florent JM, Beltra J, Dufour S, De Mendez I, Manceau P, Tertre A, Moreau F, Compere D, Dublanchet AC, O'Gara M. Crystal structures of novel non-peptidic, non-zinc chelating inhibitors bound to MMP-12. J Mol Biol. 2004 Aug 20;341(4):1063-76. PMID:15289103 doi:http://dx.doi.org/10.1016/j.jmb.2004.06.039

Page seeded by OCA on Wed Mar 4 14:48:36 2009

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OCA

[1] Pochetti G, Montanari R, Gege C, Chevrier C, Taveras AG, Mazza F. Extra Binding Region Induced by Non-Zinc Chelating Inhibitors into the S(1)' Subsite of Matrix Metalloproteinase 8 (MMP-8) (dagger). J Med Chem. 2009 Jan 27. PMID:19173605 doi:http://dx.doi.org/10.1021/jm801166j

[2] Wasserman ZR. Making a new turn in matrix metalloprotease inhibition. Chem Biol. 2005 Feb;12(2):143-4. PMID:15734640 doi:http://dx.doi.org/10.1016/j.chembiol.2005.01.008

[3] Johnson AR, Pavlovsky AG, Ortwine DF, Prior F, Man CF, Bornemeier DA, Banotai CA, Mueller WT, McConnell P, Yan C, Baragi V, Lesch C, Roark WH, Wilson M, Datta K, Guzman R, Han HK, Dyer RD. Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects. J Biol Chem. 2007 Sep 21;282(38):27781-91. Epub 2007 Jul 10. PMID:17623656 doi:http://dx.doi.org/10.1074/jbc.M703286200

[4] Morales R, Perrier S, Florent JM, Beltra J, Dufour S, De Mendez I, Manceau P, Tertre A, Moreau F, Compere D, Dublanchet AC, O'Gara M. Crystal structures of novel non-peptidic, non-zinc chelating inhibitors bound to MMP-12. J Mol Biol. 2004 Aug 20;341(4):1063-76. PMID:15289103 doi:http://dx.doi.org/10.1016/j.jmb.2004.06.039

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-'''Unreleased structure'''
+{{Seed}}
+[[Image:3dpf.jpg|left|200px]]
-The entry 3dpf is ON HOLD  until Paper Publication
+<!--
+The line below this paragraph, containing "STRUCTURE_3dpf", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_3dpf|  PDB=3dpf  |  SCENE=  }}
-Authors: Pochetti, G., Montanari, R., Gege, C., Chevrier, C., Taveras, A.G., Mazza, F.
+===Crystal structure of the complex between MMP-8 and a non-zinc chelating inhibitor===
-Description: Crystal structure of the complex between MMP-8 and a non-zinc chelating inhibitor
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 23 12:16:07 2008''
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_19173605}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 19173605 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_19173605}}
+==About this Structure==
+DPF is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DPF OCA].
+==Reference==
+<ref group="xtra">PMID:19173605</ref><ref group="xtra">PMID:15734640</ref><ref group="xtra">PMID:17623656</ref><ref group="xtra">PMID:15289103</ref><references group="xtra"/>
+[[Category: Homo sapiens]]
+[[Category: Neutrophil collagenase]]
+[[Category: Mazza, F.]]
+[[Category: Montanari, R.]]
+[[Category: Pochetti, G.]]
+[[Category: Calcium]]
+[[Category: Collagen degradation]]
+[[Category: Extracellular matrix]]
+[[Category: Glycoprotein]]
+[[Category: Hydrolase]]
+[[Category: Metal-binding]]
+[[Category: Metalloprotease]]
+[[Category: Non-zinc chelating inhibitor]]
+[[Category: Polymorphism]]
+[[Category: Protease]]
+[[Category: Secreted]]
+[[Category: Selective inhibition]]
+[[Category: Zinc]]
+[[Category: Zymogen]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar  4 14:48:36 2009''