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== '''Deoxyhaemoglobin''' == | == '''Deoxyhaemoglobin''' == | ||
The major oxygen-binding molecule in man, responsible for binding oxygen in the lung and transporting it to the tissues by means of circulation. | The major oxygen-binding molecule in man, responsible for binding oxygen in the lung and transporting it to the tissues by means of circulation. | ||
Haemoglobin (Hb) is an iron Fe chelate tightly binding one Fe ion in its II oxidation state where it carries the charge 2+(ferrous ion). If no oxygen molecule is bound it is called deoxyhaemoglobin. Deoxyhaemoglobin is a tetramer of two α and two β chains.The <scene name='Sandbox4/Overall_structure/2'>Overall Structure</scene> of the protein-deoxyhaemoglobin | Haemoglobin (Hb) is an iron Fe chelate tightly binding one Fe ion in its II oxidation state where it carries the charge 2+(ferrous ion). If no oxygen molecule is bound it is called deoxyhaemoglobin. Deoxyhaemoglobin is a tetramer of two α and two β chains.The <scene name='Sandbox4/Overall_structure/2'>Overall Structure</scene> of the protein-deoxyhaemoglobin is shown here. | ||
This shows the <scene name='Sandbox4/Heme_group/3'>Heme group</scene> of deoxyhaemoglobin. | This shows the <scene name='Sandbox4/Heme_group/3'>Heme group</scene> of deoxyhaemoglobin. | ||
Here is the <scene name='Sandbox4/Alpha2beta2/3'> | Here is the <scene name='Sandbox4/Alpha2beta2/3'>alpha and beta strands</scene> | ||
This is the highlighted <scene name='Sandbox4/Hydrophobic/5'>hydrophobic part</scene>. | |||
Reference: | Reference: | ||
1).[[ http://www.medcyclopaedia.com/library/topics/volume_i/d/deoxyhaemoglobin.aspx]] | 1).[[ http://www.medcyclopaedia.com/library/topics/volume_i/d/deoxyhaemoglobin.aspx]] | ||
2) http://www.proteopedia.org/wiki/index.php/Hemoglobin | |||
Revision as of 07:41, 4 March 2009
This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks!'
Name: Jamal Salah and Vishwa Shah!
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| 101m, resolution 2.07Å () | |||||||||
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| Ligands: | , , | ||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
DeoxyhaemoglobinDeoxyhaemoglobin
The major oxygen-binding molecule in man, responsible for binding oxygen in the lung and transporting it to the tissues by means of circulation. Haemoglobin (Hb) is an iron Fe chelate tightly binding one Fe ion in its II oxidation state where it carries the charge 2+(ferrous ion). If no oxygen molecule is bound it is called deoxyhaemoglobin. Deoxyhaemoglobin is a tetramer of two α and two β chains.The of the protein-deoxyhaemoglobin is shown here.
This shows the of deoxyhaemoglobin.
Here is the
This is the highlighted .
Reference: 1).[[ http://www.medcyclopaedia.com/library/topics/volume_i/d/deoxyhaemoglobin.aspx]] 2) http://www.proteopedia.org/wiki/index.php/Hemoglobin