2jmn: Difference between revisions

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==About this Structure==
==About this Structure==
2JMN is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entries  and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vks 1vks]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMN OCA].  
2JMN is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entries  and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vks 1vks]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMN OCA].  


==Reference==
==Reference==
Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue., Hua QX, Hu SQ, Frank BH, Jia W, Chu YC, Wang SH, Burke GT, Katsoyannis PG, Weiss MA, J Mol Biol. 1996 Nov 29;264(2):390-403. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8951384 8951384]
<ref group="xtra">PMID:8951384</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Burke, G T.]]
[[Category: Burke, G T.]]
[[Category: Chu, Y C.]]
[[Category: Chu, Y C.]]
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[[Category: Mutant]]
[[Category: Mutant]]


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Revision as of 21:52, 17 February 2009

File:2jmn.png

Template:STRUCTURE 2jmn

NMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structuresNMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structures

Template:ABSTRACT PUBMED 8951384

DiseaseDisease

Known disease associated with this structure: Diabetes mellitus, rare form OMIM:[176730], Hyperproinsulinemia, familial OMIM:[176730], MODY, one form OMIM:[176730]

About this StructureAbout this Structure

2JMN is a 2 chains structure of sequences from Homo sapiens. This structure supersedes the now removed PDB entries and 1vks. Full experimental information is available from OCA.

ReferenceReference

[xtra 1]

  1. Hua QX, Hu SQ, Frank BH, Jia W, Chu YC, Wang SH, Burke GT, Katsoyannis PG, Weiss MA. Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue. J Mol Biol. 1996 Nov 29;264(2):390-403. PMID:8951384 doi:10.1006/jmbi.1996.0648

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