1o4d: Difference between revisions

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==About this Structure==
==About this Structure==
1O4D is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O4D OCA].  
1O4D is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O4D OCA].  


==Reference==
==Reference==
Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors., Lange G, Lesuisse D, Deprez P, Schoot B, Loenze P, Benard D, Marquette JP, Broto P, Sarubbi E, Mandine E, J Med Chem. 2003 Nov 20;46(24):5184-95. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14613321 14613321]
<ref group="xtra">PMID:14613321</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Lange, G.]]
[[Category: Lange, G.]]
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[[Category: Sh2 domain fragment approach]]
[[Category: Sh2 domain fragment approach]]


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Revision as of 18:45, 17 February 2009

File:1o4d.png

Template:STRUCTURE 1o4d

CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU78262.CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU78262.

Template:ABSTRACT PUBMED 14613321

DiseaseDisease

Known disease associated with this structure: Colon cancer, advanced OMIM:[190090]

About this StructureAbout this Structure

1O4D is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Lange G, Lesuisse D, Deprez P, Schoot B, Loenze P, Benard D, Marquette JP, Broto P, Sarubbi E, Mandine E. Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J Med Chem. 2003 Nov 20;46(24):5184-95. PMID:14613321 doi:http://dx.doi.org/10.1021/jm020970s

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