1jr4: Difference between revisions

Revision as of 17:34, 17 February 2009

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File:1jr4.png

Template:STRUCTURE 1jr4

CATECHOL O-METHYLTRANSFERASE BISUBSTRATE-INHIBITOR COMPLEXCATECHOL O-METHYLTRANSFERASE BISUBSTRATE-INHIBITOR COMPLEX

About this StructureAbout this Structure

1JR4 is a 1 chain structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Lerner C, Ruf A, Gramlich V, Masjost B, Zurcher G, Jakob-Roetne R, Borroni E, Diederich F. X-ray Crystal Structure of a Bisubstrate Inhibitor Bound to the Enzyme Catechol-O-methyltransferase: A Dramatic Effect of Inhibitor Preorganization on Binding Affinity We thank F. Hoffmann-La Roche for generous support of this work. We are grateful to P. Malherbe for the cloning of COMT, P. Caspers for the expression of COMT, A. Cesura for enzyme purification, B. Wipf for fermentation, and H. W. Lahm for sequencing. Angew Chem Int Ed Engl. 2001 Nov 5;40(21):4040-4042. PMID:12404486

Page seeded by OCA on Tue Feb 17 16:34:19 2009

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OCA

[1] Lerner C, Ruf A, Gramlich V, Masjost B, Zurcher G, Jakob-Roetne R, Borroni E, Diederich F. X-ray Crystal Structure of a Bisubstrate Inhibitor Bound to the Enzyme Catechol-O-methyltransferase: A Dramatic Effect of Inhibitor Preorganization on Binding Affinity We thank F. Hoffmann-La Roche for generous support of this work. We are grateful to P. Malherbe for the cloning of COMT, P. Caspers for the expression of COMT, A. Cesura for enzyme purification, B. Wipf for fermentation, and H. W. Lahm for sequencing. Angew Chem Int Ed Engl. 2001 Nov 5;40(21):4040-4042. PMID:12404486

[xtra 1]

@@ Line 14: / Line 14: @@
 ==About this Structure==
-JR4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JR4 OCA].
+JR4 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JR4 OCA].
 ==Reference==
-X-ray Crystal Structure of a Bisubstrate Inhibitor Bound to the Enzyme Catechol-O-methyltransferase: A Dramatic Effect of Inhibitor Preorganization on Binding Affinity We thank F. Hoffmann-La Roche for generous support of this work. We are grateful to P. Malherbe for the cloning of COMT, P. Caspers for the expression of COMT, A. Cesura for enzyme purification, B. Wipf for fermentation, and H. W. Lahm for sequencing. , Lerner C, Ruf A, Gramlich V, Masjost B, Zurcher G, Jakob-Roetne R, Borroni E, Diederich F, Angew Chem Int Ed Engl. 2001 Nov 5;40(21):4040-4042. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12404486 12404486]
+<ref group="xtra">PMID:12404486</ref><references group="xtra"/>
 [[Category: Catechol O-methyltransferase]]
 [[Category: Rattus norvegicus]]
-[[Category: Single protein]]
 [[Category: Ruf, A.]]
 [[Category: Stihle, M.]]
@@ Line 28: / Line 27: @@
 [[Category: Transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 20:40:28 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:34:19 2009''