1gi8: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
1GI8 is a | 1GI8 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GI8 OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:11292354</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: U-plasminogen activator]] | [[Category: U-plasminogen activator]] | ||
[[Category: Elrod, K.]] | [[Category: Elrod, K.]] | ||
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[[Category: Zn+2-mediated inhibition]] | [[Category: Zn+2-mediated inhibition]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:28:18 2009'' |
Revision as of 17:28, 17 February 2009
A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITEA NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE
Template:ABSTRACT PUBMED 11292354
About this StructureAbout this Structure
1GI8 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Katz BA, Elrod K, Luong C, Rice MJ, Mackman RL, Sprengeler PA, Spencer J, Hataye J, Janc J, Link J, Litvak J, Rai R, Rice K, Sideris S, Verner E, Young W. A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site. J Mol Biol. 2001 Apr 13;307(5):1451-86. PMID:11292354 doi:http://dx.doi.org/10.1006/jmbi.2001.4516
Page seeded by OCA on Tue Feb 17 16:28:18 2009
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Pages with broken file links
- Homo sapiens
- U-plasminogen activator
- Elrod, K.
- Hatayte, J.
- Janc, J.
- Katz, B A.
- Link, J.
- Litvak, J.
- Luong, C.
- Mackman, R L.
- Rai, R.
- Rice, K.
- Rice, M.
- Sideris, S.
- Spencer, J.
- Sprengeler, P A.
- Verner, E.
- Young, W.
- Oxyanion hole water
- Shift of pka of his57
- Specificity
- Structure-based drug design
- Three-centered
- Thrombin
- Trypsin
- Urokinase
- Very short hydrogen bond
- Zn+2-mediated inhibition