3e63: Difference between revisions

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==About this Structure==
==About this Structure==
3E63 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E63 OCA].  
3E63 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E63 OCA].  


==Reference==
==Reference==
Fragment-based discovery of JAK-2 inhibitors., Antonysamy S, Hirst G, Park F, Sprengeler P, Stappenbeck F, Steensma R, Wilson M, Wong M, Bioorg Med Chem Lett. 2009 Jan 1;19(1):279-82. Epub 2008 Aug 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19019674 19019674]
<ref group="xtra">PMID:19019674</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Single protein]]
[[Category: Antonysamy, S S.]]
[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Chromosomal rearrangement]]
[[Category: Chromosomal rearrangement]]
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[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:32:03 2009''

Revision as of 14:32, 17 February 2009

File:3e63.png

Template:STRUCTURE 3e63

Fragment based discovery of JAK-2 inhibitorsFragment based discovery of JAK-2 inhibitors

Template:ABSTRACT PUBMED 19019674

DiseaseDisease

Known disease associated with this structure: Leukemia, acute myelogenous OMIM:[147796], Myelofibrosis, idiopathic OMIM:[147796], Myeloproliferative disorder with erythrocytosis OMIM:[147796], Polycythemia vera OMIM:[147796], Thrombocythemia, essential OMIM:[147796], Budd-Chiari syndrome OMIM:[147796]

About this StructureAbout this Structure

3E63 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Antonysamy S, Hirst G, Park F, Sprengeler P, Stappenbeck F, Steensma R, Wilson M, Wong M. Fragment-based discovery of JAK-2 inhibitors. Bioorg Med Chem Lett. 2009 Jan 1;19(1):279-82. Epub 2008 Aug 22. PMID:19019674 doi:10.1016/j.bmcl.2008.08.064

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