2pl0: Difference between revisions

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==About this Structure==
==About this Structure==
2PL0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PL0 OCA].  
2PL0 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PL0 OCA].  


==Reference==
==Reference==
Classifying protein kinase structures guides use of ligand-selectivity profiles to predict inactive conformations: Structure of lck/imatinib complex., Jacobs MD, Caron PR, Hare BJ, Proteins. 2007 Oct 1;70(4):1451-1460. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17910071 17910071]
<ref group="xtra">PMID:17910071</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Single protein]]
[[Category: Jacobs, M D.]]
[[Category: Jacobs, M D.]]
[[Category: Kinase phosphorylation]]
[[Category: Kinase phosphorylation]]
[[Category: Transferase]]
[[Category: Transferase]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:23:36 2009''

Revision as of 03:23, 17 February 2009

File:2pl0.png

Template:STRUCTURE 2pl0

LCK bound to imatinibLCK bound to imatinib

Template:ABSTRACT PUBMED 17910071

DiseaseDisease

Known disease associated with this structure: SCID due to LCK deficiency OMIM:[153390]

About this StructureAbout this Structure

2PL0 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Jacobs MD, Caron PR, Hare BJ. Classifying protein kinase structures guides use of ligand-selectivity profiles to predict inactive conformations: Structure of lck/imatinib complex. Proteins. 2007 Oct 1;70(4):1451-1460. PMID:17910071 doi:10.1002/prot.21633

Page seeded by OCA on Tue Feb 17 02:23:36 2009

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