2fde: Difference between revisions

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==About this Structure==
==About this Structure==
2FDE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FDE OCA].  
2FDE is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FDE OCA].  


==Reference==
==Reference==
Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: the discovery of GW0385., Miller JF, Andrews CW, Brieger M, Furfine ES, Hale MR, Hanlon MH, Hazen RJ, Kaldor I, McLean EW, Reynolds D, Sammond DM, Spaltenstein A, Tung R, Turner EM, Xu RX, Sherrill RG, Bioorg Med Chem Lett. 2006 Apr 1;16(7):1788-94. Epub 2006 Feb 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16458505 16458505]
<ref group="xtra">PMID:16458505</ref><references group="xtra"/>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Single protein]]
[[Category: Xu, R X.]]
[[Category: Xu, R X.]]
[[Category: Gw0385]]
[[Category: Gw0385]]
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[[Category: Inhibitor]]
[[Category: Inhibitor]]


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Revision as of 01:39, 17 February 2009

File:2fde.png

Template:STRUCTURE 2fde

Wild type HIV protease bound with GW0385Wild type HIV protease bound with GW0385

Template:ABSTRACT PUBMED 16458505

About this StructureAbout this Structure

2FDE is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Miller JF, Andrews CW, Brieger M, Furfine ES, Hale MR, Hanlon MH, Hazen RJ, Kaldor I, McLean EW, Reynolds D, Sammond DM, Spaltenstein A, Tung R, Turner EM, Xu RX, Sherrill RG. Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: the discovery of GW0385. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1788-94. Epub 2006 Feb 3. PMID:16458505 doi:10.1016/j.bmcl.2006.01.035

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