3b3n: Difference between revisions

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==About this Structure==
==About this Structure==
3B3N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B3N OCA].  
3B3N is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B3N OCA].  


==Reference==
==Reference==
Minimal pharmacophoric elements and fragment hopping, an approach directed at molecular diversity and isozyme selectivity. Design of selective neuronal nitric oxide synthase inhibitors., Ji H, Stanton BZ, Igarashi J, Li H, Martasek P, Roman LJ, Poulos TL, Silverman RB, J Am Chem Soc. 2008 Mar 26;130(12):3900-14. Epub 2008 Mar 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18321097 18321097]
<ref group="xtra">PMID:18321097</ref><references group="xtra"/>
[[Category: Nitric-oxide synthase]]
[[Category: Nitric-oxide synthase]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Igarashi, J.]]
[[Category: Igarashi, J.]]
[[Category: Li, H.]]
[[Category: Li, H.]]
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[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]


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Revision as of 23:10, 16 February 2009

File:3b3n.png

Template:STRUCTURE 3b3n

Structure of neuronal NOS heme domain in complex with a inhibitor (+-)-N1-{cis-4'-[(6"-aminopyridin-2"-yl)methyl]pyrrolidin-3'-yl}ethane-1,2-diamine

Template:ABSTRACT PUBMED 18321097

About this StructureAbout this Structure

3B3N is a 2 chains structure of sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Ji H, Stanton BZ, Igarashi J, Li H, Martasek P, Roman LJ, Poulos TL, Silverman RB. Minimal pharmacophoric elements and fragment hopping, an approach directed at molecular diversity and isozyme selectivity. Design of selective neuronal nitric oxide synthase inhibitors. J Am Chem Soc. 2008 Mar 26;130(12):3900-14. Epub 2008 Mar 6. PMID:18321097 doi:10.1021/ja0772041

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