1n56: Difference between revisions

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[[Image:1n56.gif|left|200px]]
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{{STRUCTURE_1n56|  PDB=1n56  |  SCENE=  }}  
{{STRUCTURE_1n56|  PDB=1n56  |  SCENE=  }}  


'''Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion'''
===Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion===


==Overview==
Studies on several recently discovered error-prone DNA polymerases reveal novel structures that may explain the low fidelity of this general class of enzymes, a number of which are involved in the replicative bypass (translesion synthesis) of base damage in DNA.


==About this Structure==
==About this Structure==
1N56 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N56 OCA].  
1N56 is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N56 OCA].  


==Reference==
==Reference==
Error-prone DNA polymerases: novel structures and the benefits of infidelity., Friedberg EC, Fischhaber PL, Kisker C, Cell. 2001 Oct 5;107(1):9-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11595180 11595180]
<ref group="xtra">PMID:11595180</ref><references group="xtra"/>
[[Category: Single protein]]
[[Category: Sulfolobus solfataricus]]
[[Category: Sulfolobus solfataricus]]
[[Category: Boudsocq, F.]]
[[Category: Boudsocq, F.]]
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[[Category: Protein-dna complex]]
[[Category: Protein-dna complex]]
[[Category: Y-family]]
[[Category: Y-family]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 02:06:34 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 11:40:47 2009''

Revision as of 12:40, 16 February 2009

File:1n56.png

Template:STRUCTURE 1n56

Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesionY-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion

About this StructureAbout this Structure

1N56 is a 6 chains structure of sequences from Sulfolobus solfataricus. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Friedberg EC, Fischhaber PL, Kisker C. Error-prone DNA polymerases: novel structures and the benefits of infidelity. Cell. 2001 Oct 5;107(1):9-12. PMID:11595180

Page seeded by OCA on Mon Feb 16 11:40:47 2009

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