3faa: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3faa.jpg|left|200px]]


The entry 3faa is ON HOLD until Paper Publication
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{{STRUCTURE_3faa|  PDB=3faa  |  SCENE=  }}


Authors: Boriack-Sjodin, P.A., Fitch, C.
===Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor===


Description: Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 14:40:08 2008''
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{{ABSTRACT_PUBMED_19135364}}
 
==Disease==
Known disease associated with this structure: Loeys-Dietz syndrome, type 1A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190181 190181]], Loeys-Dietz syndrome, type 2A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190181 190181]]
 
==About this Structure==
3FAA is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FAA OCA].
 
==Reference==
<ref group="xtra">PMID:19135364</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Receptor protein serine/threonine kinase]]
[[Category: Boriack-Sjodin, P A.]]
[[Category: Fitch, C.]]
[[Category: Atp-binding]]
[[Category: Craniosynostosis]]
[[Category: Disease mutation]]
[[Category: Glycoprotein]]
[[Category: Kinase]]
[[Category: Magnesium]]
[[Category: Manganese]]
[[Category: Membrane]]
[[Category: Metal-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Protein-inhibitor complex]]
[[Category: Receptor]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Structure-based drug design]]
[[Category: Tgfbeta]]
[[Category: Transferase]]
[[Category: Transmembrane]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 28 09:55:14 2009''

Revision as of 10:55, 28 January 2009

File:3faa.jpg

Template:STRUCTURE 3faa

Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitorCrystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor

Template:ABSTRACT PUBMED 19135364

DiseaseDisease

Known disease associated with this structure: Loeys-Dietz syndrome, type 1A OMIM:[190181], Loeys-Dietz syndrome, type 2A OMIM:[190181]

About this StructureAbout this Structure

3FAA is a 5 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. ↑ Bonafoux D, Chuaqui C, Boriack-Sjodin PA, Fitch C, Hankins G, Josiah S, Black C, Hetu G, Ling L, Lee WC. 2-Aminoimidazoles inhibitors of TGF-beta receptor 1. Bioorg Med Chem Lett. 2009 Feb 1;19(3):912-6. Epub 2008 Dec 11. PMID:19135364 doi:10.1016/j.bmcl.2008.11.119

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