Lactose Permease: Difference between revisions
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===Function of Lactose Permease=== | |||
[[Image:(image info)|left|(Caption)]] Lactose Permease is a transmembrane protein that | [[Image:(image info)|left|(Caption)]] Lactose Permease is a transmembrane protein that | ||
facilitates the passage of lactose across the phospholipid bi-layer of the cell membrane. The | facilitates the passage of lactose across the phospholipid bi-layer of the cell membrane. The | ||
transport mechanism used is an active co-transport that uses the inwardly directed H+ | transport mechanism used is an active co-transport that uses the inwardly directed H+ | ||
electrochemical gradient as its driving force. As a result, the lactose is accompanied from | electrochemical gradient as its driving force. As a result, the lactose is accompanied from | ||
the periplasm to the cytoplasm of the cell by an H+ proton. | the periplasm to the cytoplasm of the cell by an H+ proton. | ||
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process of cellular respiration. | process of cellular respiration. | ||
===Structure of Lactose Permease=== | |||
<applet load="1PV7" size="300" color="white" frame="true" align="right" caption="Lactose Permease" /> | <applet load="1PV7" size="300" color="white" frame="true" align="right" caption="Lactose Permease" /> | ||
Lactose permease is a transmembrane protien consisting of N- and C- terminal domains, each with <Scene> six transmembrane helices, symmetrically positioned within the permease. Six side chains have been determined to be irreplaceable with respect to active transport of | Lactose permease is a transmembrane protien consisting of N- and C- terminal domains, each with <Scene> six transmembrane helices, symmetrically positioned within the permease. Six side chains have been determined to be irreplaceable with respect to active transport of | ||
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conformation, in which the large hydrophilic cavity discussed previously is oriented towards | conformation, in which the large hydrophilic cavity discussed previously is oriented towards | ||
the cytoplasm, has been crystallized thus far. | the cytoplasm, has been crystallized thus far. | ||
Replace the PDB id after the STRUCTURE_ and after PDB= to load | Replace the PDB id after the STRUCTURE_ and after PDB= to load | ||
and display another structure. | and display another structure. | ||