3ekk: Difference between revisions
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Revision as of 09:10, 7 January 2009
Insulin receptor kinase complexed with an inhibitorInsulin receptor kinase complexed with an inhibitor
Template:ABSTRACT PUBMED 19056263
DiseaseDisease
Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[147670], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[147670], Leprechaunism OMIM:[147670], Rabson-Mendenhall syndrome OMIM:[147670]
About this StructureAbout this Structure
3EKK is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase., Chamberlain SD, Wilson JW, Deanda F, Patnaik S, Redman AM, Yang B, Shewchuk L, Sabbatini P, Leesnitzer MA, Groy A, Atkins C, Gerding R, Hassell AM, Lei H, Mook RA Jr, Moorthy G, Rowand JL, Stevens KL, Kumar R, Shotwell JB, Bioorg Med Chem Lett. 2008 Nov 18. PMID:19056263
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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCA- Pages with broken file links
- Homo sapiens
- Receptor protein-tyrosine kinase
- Atkins, C.
- Chamberlain, S.
- Deanda, F.
- Dumble, M.
- Gerding, R.
- Groy, A.
- Korenchuk, S.
- Kumar, R.
- Lei, H.
- Mook, R.
- Moorthy, G.
- Redman, A.
- Rowland, J.
- Sabbatini, P.
- Shewchuk, L.
- Alternative splicing
- Atp-binding
- Carbohydrate metabolism
- Cleavage on pair of basic residue
- Diabetes mellitus
- Disease mutation
- Glycoprotein
- Insulin
- Kinase
- Membrane
- Nucleotide-binding
- Phosphoprotein
- Polymorphism
- Receptor
- Transferase
- Transmembrane
- Tyrosine kinase
- Tyrosine-protein kinase