3br9: Difference between revisions

Revision as of 12:29, 24 December 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:3br9.jpg

Template:STRUCTURE 3br9

Crystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone InhibitorCrystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone Inhibitor

Template:ABSTRACT PUBMED 18242088

About this StructureAbout this Structure

3BR9 is a 2 chains structure of sequences from Hepatitis c virus. Full crystallographic information is available from OCA.

ReferenceReference

Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5- hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine., Zhou Y, Webber SE, Murphy DE, Li LS, Dragovich PS, Tran CV, Sun Z, Ruebsam F, Shah AM, Tsan M, Showalter RE, Patel R, Li B, Zhao Q, Han Q, Hermann T, Kissinger CR, Lebrun L, Sergeeva MV, Kirkovsky L, Bioorg Med Chem Lett. 2008 Feb 15;18(4):1413-8. Epub 2008 Jan 8. PMID:18242088

Page seeded by OCA on Wed Dec 24 11:29:09 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Unreleased structure'''
+{{Seed}}
+[[Image:3br9.jpg|left|200px]]
-The entry 3br9 is ON HOLD  until Dec 21 2009
+<!--
+The line below this paragraph, containing "STRUCTURE_3br9", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_3br9|  PDB=3br9  |  SCENE=  }}
-Authors: Zhao, Q., Showalter, R.E., Han, Q., Kissinger, C.R.
+===Crystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone Inhibitor===
-Description: Crystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone Inhibitor
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_18242088}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 18242088 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_18242088}}
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 09:27:46 2008''
+==About this Structure==
+BR9 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BR9 OCA].
+==Reference==
+Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5- hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine., Zhou Y, Webber SE, Murphy DE, Li LS, Dragovich PS, Tran CV, Sun Z, Ruebsam F, Shah AM, Tsan M, Showalter RE, Patel R, Li B, Zhao Q, Han Q, Hermann T, Kissinger CR, Lebrun L, Sergeeva MV, Kirkovsky L, Bioorg Med Chem Lett. 2008 Feb 15;18(4):1413-8. Epub 2008 Jan 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18242088 18242088]
+[[Category: Hepatitis c virus]]
+[[Category: RNA-directed RNA polymerase]]
+[[Category: Han, Q.]]
+[[Category: Kissinger, C R.]]
+[[Category: Showalter, R E.]]
+[[Category: Zhao, Q.]]
+[[Category: Antiviral]]
+[[Category: Cytoplasm]]
+[[Category: Host-virus interaction]]
+[[Category: Hydrolase]]
+[[Category: Metal-binding]]
+[[Category: Nucleotide-binding]]
+[[Category: Nucleotidyltransferase]]
+[[Category: Protein-ligand complex]]
+[[Category: Ribonucleoprotein]]
+[[Category: Rna replication]]
+[[Category: Rna-binding]]
+[[Category: Rna-directed rna polymerase]]
+[[Category: Transcription]]
+[[Category: Transcription regulation]]
+[[Category: Transferase]]
+[[Category: Viral nucleoprotein]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 24 11:29:09 2008''